Comparative study of the morphological changes in lymphocytes of elderly individuals and centenarians. Export

@article{citeulike:5930983, abstract = {The number of white blood cells, the morphological changes of the peripheral lymphocytes and some immunological variables were examined in 118 centenarians and in 499 healthy subjects of 60-89 years of age. There was no change in the absolute number of leucocytes, lymphocytes, or T or B cells with age. The occurrence of a myelin-like structure in the mitochondria and the presence of lipofuscin in the cytoplasm of lymphocytes increased with age and showed a correlation with the absolute number of T cells. A correlation could be observed between the absolute number of B cells, serum IgG level and the presence of antinuclear factor.}, author = {Beregi, E. and Regius, O. and Rajczy, K.}, citeulike-article-id = {5930983}, citeulike-linkout-0 = {http://view.ncbi.nlm.nih.gov/pubmed/1851378}, citeulike-linkout-1 = {http://www.hubmed.org/display.cgi?uids=1851378}, issn = {0002-0729}, journal = {Age and ageing}, keywords = {age-changes, immunosenescence, lymphocyte, senescence}, month = {January}, number = {1}, pages = {55--59}, posted-at = {2009-10-12 22:20:44}, priority = {2}, title = {Comparative study of the morphological changes in lymphocytes of elderly individuals and centenarians.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/1851378}, volume = {20}, year = {1991} }

TY - JOUR ID - citeulike:5930983 L3 - citeulike-article-id:5930983 N2 - The number of white blood cells, the morphological changes of the peripheral lymphocytes and some immunological variables were examined in 118 centenarians and in 499 healthy subjects of 60-89 years of age. There was no change in the absolute number of leucocytes, lymphocytes, or T or B cells with age. The occurrence of a myelin-like structure in the mitochondria and the presence of lipofuscin in the cytoplasm of lymphocytes increased with age and showed a correlation with the absolute number of T cells. A correlation could be observed between the absolute number of B cells, serum IgG level and the presence of antinuclear factor. IS - 1 JF - Age and ageing SN - 0002-0729 EP - 59 TI - Comparative study of the morphological changes in lymphocytes of elderly individuals and centenarians. VL - 20 SP - 55 KW - age-changes KW - immunosenescence KW - lymphocyte KW - senescence AU - Beregi, E AU - Regius, O AU - Rajczy, K PY - 1991/01// UR - http://view.ncbi.nlm.nih.gov/pubmed/1851378 ER -