Biofilm formation as microbial development. Export

@article{citeulike:2820369, abstract = {Biofilms can be defined as communities of microorganisms attached to a surface. It is clear that microorganisms undergo profound changes during their transition from planktonic (free-swimming) organisms to cells that are part of a complex, surface-attached community. These changes are reflected in the new phenotypic characteristics developed by biofilm bacteria and occur in response to a variety of environmental signals. Recent genetic and molecular approaches used to study bacterial and fungal biofilms have identified genes and regulatory circuits important for initial cell-surface interactions, biofilm maturation, and the return of biofilm microorganisms to a planktonic mode of growth. Studies to date suggest that the planktonic-biofilm transition is a complex and highly regulated process. The results reviewed in this article indicate that the formation of biofilms serves as a new model system for the study of microbial development.}, address = {Department of Microbiology, Dartmouth Medical School, Hanover, New Hampshire 03755, USA. georgeo@Dartmouth.edu}, author = {O'Toole, G. and Kaplan, H. B. and Kolter, R.}, citeulike-article-id = {2820369}, citeulike-linkout-0 = {http://arjournals.annualreviews.org/doi/abs/10.1146/annurev.micro.54.1.49}, citeulike-linkout-1 = {http://dx.doi.org/10.1146/annurev.micro.54.1.49}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/11018124}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=11018124}, doi = {10.1146/annurev.micro.54.1.49}, issn = {0066-4227}, journal = {Annual review of microbiology}, keywords = {bacteria, biofilms, review, surface}, number = {1}, pages = {49--79}, posted-at = {2009-09-29 13:33:20}, priority = {2}, title = {Biofilm formation as microbial development.}, url = {http://dx.doi.org/10.1146/annurev.micro.54.1.49}, volume = {54}, year = {2000} }

TY - JOUR ID - citeulike:2820369 L3 - citeulike-article-id:2820369 N2 - Biofilms can be defined as communities of microorganisms attached to a surface. It is clear that microorganisms undergo profound changes during their transition from planktonic (free-swimming) organisms to cells that are part of a complex, surface-attached community. These changes are reflected in the new phenotypic characteristics developed by biofilm bacteria and occur in response to a variety of environmental signals. Recent genetic and molecular approaches used to study bacterial and fungal biofilms have identified genes and regulatory circuits important for initial cell-surface interactions, biofilm maturation, and the return of biofilm microorganisms to a planktonic mode of growth. Studies to date suggest that the planktonic-biofilm transition is a complex and highly regulated process. The results reviewed in this article indicate that the formation of biofilms serves as a new model system for the study of microbial development. IS - 1 JF - Annual review of microbiology SN - 0066-4227 AD - Department of Microbiology, Dartmouth Medical School, Hanover, New Hampshire 03755, USA. georgeo@Dartmouth.edu EP - 79 TI - Biofilm formation as microbial development. VL - 54 SP - 49 KW - bacteria KW - biofilms KW - review KW - surface AU - O'Toole, G AU - Kaplan, HB AU - Kolter, R PY - 2000/// UR - http://dx.doi.org/10.1146/annurev.micro.54.1.49 ER -