Non-synaptic dendritic spines in neocortex.

by: JI Arellano, A Espinosa, A Fairén, R Yuste, J DeFelipe

Neuroscience, Vol. 145, No. 2. (16 March 2007), pp. 464-469.

View FullText article

DOI, Pubmed, Hubmed

Reviews [Write a review of this article]

There are no reviews of this article

Find related articles from these CiteULike users

agidon20

Find related articles with these CiteULike tags

connectivity

Abstract

A long-held assumption states that each dendritic spine in the cerebral cortex forms a synapse, although this issue has not been systematically investigated. We performed complete ultrastructural reconstructions of a large (n=144) population of identified spines in adult mouse neocortex finding that only 3.6% of the spines clearly lacked synapses. Nonsynaptic spines were small and had no clear head, resembling dendritic filopodia, and could represent a source of new synaptic connections in the adult cerebral cortex.

@article{citeulike:2815779, abstract = {A long-held assumption states that each dendritic spine in the cerebral cortex forms a synapse, although this issue has not been systematically investigated. We performed complete ultrastructural reconstructions of a large (n=144) population of identified spines in adult mouse neocortex finding that only 3.6\% of the spines clearly lacked synapses. Nonsynaptic spines were small and had no clear head, resembling dendritic filopodia, and could represent a source of new synaptic connections in the adult cerebral cortex.}, address = {Departamento de Neuroanatomia y Biologia Celular, Instituto Cajal (CSIC), Ave. Dr. Arce, 37, 28002 Madrid, Spain.}, author = {Arellano, J. I. and Espinosa, A. and Fair\'{e}n, A. and Yuste, R. and DeFelipe, J. }, citeulike-article-id = {2815779}, doi = {10.1016/j.neuroscience.2006.12.015}, issn = {0306-4522}, journal = {Neuroscience}, keywords = {connectivity}, month = {March}, number = {2}, pages = {464--469}, posted-at = {2008-05-20 13:59:51}, priority = {2}, title = {Non-synaptic dendritic spines in neocortex.}, url = {http://dx.doi.org/10.1016/j.neuroscience.2006.12.015}, volume = {145}, year = {2007} }

RIS record

TY - JOUR ID - citeulike:2815779 L3 - citeulike-article-id:2815779 TI - Non-synaptic dendritic spines in neocortex. JF - Neuroscience VL - 145 IS - 2 SP - 464 EP - 469 AD - Departamento de Neuroanatomia y Biologia Celular, Instituto Cajal (CSIC), Ave. Dr. Arce, 37, 28002 Madrid, Spain. SN - 0306-4522 N2 - A long-held assumption states that each dendritic spine in the cerebral cortex forms a synapse, although this issue has not been systematically investigated. We performed complete ultrastructural reconstructions of a large (n=144) population of identified spines in adult mouse neocortex finding that only 3.6% of the spines clearly lacked synapses. Nonsynaptic spines were small and had no clear head, resembling dendritic filopodia, and could represent a source of new synaptic connections in the adult cerebral cortex. KW - connectivity AU - Arellano, JI AU - Espinosa, A AU - Fairén, A AU - Yuste, R AU - DeFelipe, J PY - 2007/03/16/ UR - http://dx.doi.org/10.1016/j.neuroscience.2006.12.015 ER -

RIS BibTeX