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A Novel Automated Mammographic Density Measure and Breast Cancer Risk

by: John J. Heine, Christopher G. Scott, Thomas A. Sellers, Kathleen R. Brandt, Daniel J. Serie, Fang-Fang Wu, Marilyn J. Morton, Beth A. Schueler, Fergus J. Couch, Janet E. Olson, V. Shane Pankratz, Celine M. Vachon
Journal of the National Cancer Institute, Vol. 104, No. 13. (03 July 2012), pp. 1028-1037, doi:10.1093/jnci/djs254  Key: citeulike:11057215

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Abstract

Background Mammographic breast density is a strong breast cancer risk factor but is not used in the clinical setting, partly because of a lack of standardization and automation. We developed an automated and objective measurement of the grayscale value variation within a mammogram, evaluated its association with breast cancer, and compared its performance with that of percent density (PD).


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