DrugBank: a knowledgebase for drugs, drug actions and drug targets. Export

@article{citeulike:2191303, abstract = {DrugBank is a richly annotated resource that combines detailed drug data with comprehensive drug target and drug action information. Since its first release in 2006, DrugBank has been widely used to facilitate in silico drug target discovery, drug design, drug docking or screening, drug metabolism prediction, drug interaction prediction and general pharmaceutical education. The latest version of DrugBank (release 2.0) has been expanded significantly over the previous release. With approximately 4900 drug entries, it now contains 60\% more FDA-approved small molecule and biotech drugs including 10\% more 'experimental' drugs. Significantly, more protein target data has also been added to the database, with the latest version of DrugBank containing three times as many non-redundant protein or drug target sequences as before (1565 versus 524). Each DrugCard entry now contains more than 100 data fields with half of the information being devoted to drug/chemical data and the other half devoted to pharmacological, pharmacogenomic and molecular biological data. A number of new data fields, including food-drug interactions, drug-drug interactions and experimental ADME data have been added in response to numerous user requests. DrugBank has also significantly improved the power and simplicity of its structure query and text query searches. DrugBank is available at http://www.drugbank.ca.}, author = {Wishart, David S. and Knox, Craig and Guo, An C. and Cheng, Dean and Shrivastava, Savita and Tzur, Dan and Gautam, Bijaya and Hassanali, Murtaza}, citeulike-article-id = {2191303}, citeulike-linkout-0 = {http://dx.doi.org/10.1093/nar/gkm958}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/18048412}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=18048412}, citeulike-linkout-3 = {http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=18048412}, day = {11}, doi = {10.1093/nar/gkm958}, issn = {1362-4962}, journal = {Nucleic acids research}, keywords = {anti-tnf, cheminformatics, database, drugs\_search, neutraceutical, ra}, month = {January}, number = {Database issue}, pages = {D901--D906}, posted-at = {2009-06-23 17:17:11}, priority = {2}, title = {DrugBank: a knowledgebase for drugs, drug actions and drug targets.}, url = {http://dx.doi.org/10.1093/nar/gkm958}, volume = {36 (Database issue)}, year = {2008} }

TY - JOUR ID - citeulike:2191303 L3 - citeulike-article-id:2191303 N2 - DrugBank is a richly annotated resource that combines detailed drug data with comprehensive drug target and drug action information. Since its first release in 2006, DrugBank has been widely used to facilitate in silico drug target discovery, drug design, drug docking or screening, drug metabolism prediction, drug interaction prediction and general pharmaceutical education. The latest version of DrugBank (release 2.0) has been expanded significantly over the previous release. With approximately 4900 drug entries, it now contains 60% more FDA-approved small molecule and biotech drugs including 10% more 'experimental' drugs. Significantly, more protein target data has also been added to the database, with the latest version of DrugBank containing three times as many non-redundant protein or drug target sequences as before (1565 versus 524). Each DrugCard entry now contains more than 100 data fields with half of the information being devoted to drug/chemical data and the other half devoted to pharmacological, pharmacogenomic and molecular biological data. A number of new data fields, including food-drug interactions, drug-drug interactions and experimental ADME data have been added in response to numerous user requests. DrugBank has also significantly improved the power and simplicity of its structure query and text query searches. DrugBank is available at http://www.drugbank.ca. IS - Database issue JF - Nucleic acids research SN - 1362-4962 EP - D906 TI - DrugBank: a knowledgebase for drugs, drug actions and drug targets. VL - 36 (Database issue) SP - D901 KW - anti-tnf KW - cheminformatics KW - database KW - drugs_search KW - neutraceutical KW - ra AU - Wishart, David AU - Knox, Craig AU - Guo, An AU - Cheng, Dean AU - Shrivastava, Savita AU - Tzur, Dan AU - Gautam, Bijaya AU - Hassanali, Murtaza PY - 2008/01/11/ UR - http://dx.doi.org/10.1093/nar/gkm958 ER -