Characterizing function–structure relationships in the human visual system with functional MRI and diffusion tensor imaging Export

@article{relationship:function-structure, abstract = {A key objective in neuroscience is to improve our understanding of the relationship between brain function and structure. We investigated this in the posterior visual pathways of healthy volunteers by applying functional magnetic resonance imaging (fMRI) and diffusion tensor imaging (DTI) with tractography. The optic radiations were segmented using the Probabilistic Index of Connectivity (PICo) tractography algorithm and extracted at several thresholds of connection confidence. The mean fractional anisotropy (FA) of the estimated tracts was found to correlate significantly with fMRI measures of visual cortex activity (induced by a photic stimulation paradigm). The results support the hypothesis that the visual cortical fMRI response is constrained by the external anatomical connections of the subserving optic radiations.}, author = {TOOSY,, A and CICCARELLI,, O and PARKER,, G and WHEELERKINGSHOTT,, C and MILLER,, D and THOMPSON,, A}, citeulike-article-id = {3284979}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.neuroimage.2003.11.022}, citeulike-linkout-1 = {http://linkinghub.elsevier.com/retrieve/pii/S1053811903007638}, citeulike-linkout-2 = {http://www.sciencedirect.com/science/article/B6WNP-4BV452M-1/2/4634ace9282eb3a0de2117262982f382}, doi = {10.1016/j.neuroimage.2003.11.022}, issn = {10538119}, journal = {NeuroImage}, keywords = {algorithm, analysis, diffusion, vision}, month = {April}, number = {4}, pages = {1452--1463}, posted-at = {2008-09-18 09:36:18}, priority = {2}, title = {Characterizing function–structure relationships in the human visual system with functional MRI and diffusion tensor imaging}, url = {http://dx.doi.org/10.1016/j.neuroimage.2003.11.022}, volume = {21}, year = {2004} }

TY - JOUR ID - relationship:function-structure L3 - citeulike-article-id:3284979 N2 - A key objective in neuroscience is to improve our understanding of the relationship between brain function and structure. We investigated this in the posterior visual pathways of healthy volunteers by applying functional magnetic resonance imaging (fMRI) and diffusion tensor imaging (DTI) with tractography. The optic radiations were segmented using the Probabilistic Index of Connectivity (PICo) tractography algorithm and extracted at several thresholds of connection confidence. The mean fractional anisotropy (FA) of the estimated tracts was found to correlate significantly with fMRI measures of visual cortex activity (induced by a photic stimulation paradigm). The results support the hypothesis that the visual cortical fMRI response is constrained by the external anatomical connections of the subserving optic radiations. IS - 4 JF - NeuroImage SN - 10538119 EP - 1463 TI - Characterizing function–structure relationships in the human visual system with functional MRI and diffusion tensor imaging VL - 21 SP - 1452 KW - algorithm KW - analysis KW - diffusion KW - vision AU - TOOSY,, A AU - CICCARELLI,, O AU - PARKER,, G AU - WHEELERKINGSHOTT,, C AU - MILLER,, D AU - THOMPSON,, A PY - 2004/04// UR - http://dx.doi.org/10.1016/j.neuroimage.2003.11.022 ER -