Repeated administration of 5-methoxy-N,N-dimethyltryptamine to male rats potentiates stimulation of prolactine secretino by serotonin agonists Export

@article{citeulike:3771961, abstract = {Repeated administration of 5-methoxy-N,N-demethyltryptamine (5MeODMT, 5 mg/kg, a serotonin agonist, every 3 h for a total of 4 injections) potentiated its prolactin (PRL)-releasing effect and that of two other serotonin agonists, quipazine and N,N-dimethyltryptamine. This pretreatment schedule had no effect on PRL response to anti-dopaminergic drugs. The onset of enhanced PRL response to serotonin agonists was gradual and appears to be due to sensitization of the serotonergic mechanism involved in the regulation of PRL secretion. The possible mechanisms underlying this phenomenon are discussed.}, author = {Simonovic, M.}, citeulike-article-id = {3771961}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/0014-2999(79)90310-8}, citeulike-linkout-1 = {http://linkinghub.elsevier.com/retrieve/pii/0014-2999(79)90310-8}, day = {15}, doi = {10.1016/0014-2999(79)90310-8}, issn = {00142999}, journal = {European Journal of Pharmacology}, keywords = {5-meo-dmt, 5ht, prolactin}, month = {October}, number = {4}, pages = {399--405}, posted-at = {2008-12-11 00:39:36}, priority = {2}, title = {Repeated administration of 5-methoxy-N,N-dimethyltryptamine to male rats potentiates stimulation of prolactine secretino by serotonin agonists}, url = {http://dx.doi.org/10.1016/0014-2999(79)90310-8}, volume = {58}, year = {1979} }

TY - JOUR ID - citeulike:3771961 L3 - citeulike-article-id:3771961 N2 - Repeated administration of 5-methoxy-N,N-demethyltryptamine (5MeODMT, 5 mg/kg, a serotonin agonist, every 3 h for a total of 4 injections) potentiated its prolactin (PRL)-releasing effect and that of two other serotonin agonists, quipazine and N,N-dimethyltryptamine. This pretreatment schedule had no effect on PRL response to anti-dopaminergic drugs. The onset of enhanced PRL response to serotonin agonists was gradual and appears to be due to sensitization of the serotonergic mechanism involved in the regulation of PRL secretion. The possible mechanisms underlying this phenomenon are discussed. IS - 4 JF - European Journal of Pharmacology SN - 00142999 EP - 405 TI - Repeated administration of 5-methoxy-N,N-dimethyltryptamine to male rats potentiates stimulation of prolactine secretino by serotonin agonists VL - 58 SP - 399 KW - 5-meo-dmt KW - 5ht KW - prolactin AU - Simonovic, M PY - 1979/10/15/ UR - http://dx.doi.org/10.1016/0014-2999(79)90310-8 ER -