Raphe neurons: firing rate correlates with size of drug response. Export

@article{citeulike:4981110, abstract = {Significant negative correlations were obtained between the spontaneous discharge rate during waking and the neural response to systemic injections of either 5-MeODMT or LSD for serotonergic neurons in the dorsal raphe nucleus, nucleus centralis superior, and nucleus raphe pallidus of unanesthetized and unrestrained cats. These data are discussed in terms of an hypothesis which accounts for both the rate of spontaneous activity of serotonergic neurons and the magnitude of their response to serotonin agonist drugs in terms of autoreceptor density on individual neurons.}, author = {Jacobs, B. L. and Heym, J. and Rasmussen, K.}, citeulike-article-id = {4981110}, citeulike-linkout-0 = {http://view.ncbi.nlm.nih.gov/pubmed/6873185}, citeulike-linkout-1 = {http://www.hubmed.org/display.cgi?uids=6873185}, day = {3}, issn = {0014-2999}, journal = {European journal of pharmacology}, keywords = {5-meodmt, 5ht, dorsal, lsd, raphe}, month = {June}, number = {2-3}, pages = {275--278}, posted-at = {2009-06-26 19:13:14}, priority = {2}, title = {Raphe neurons: firing rate correlates with size of drug response.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/6873185}, volume = {90}, year = {1983} }

TY - JOUR ID - citeulike:4981110 L3 - citeulike-article-id:4981110 N2 - Significant negative correlations were obtained between the spontaneous discharge rate during waking and the neural response to systemic injections of either 5-MeODMT or LSD for serotonergic neurons in the dorsal raphe nucleus, nucleus centralis superior, and nucleus raphe pallidus of unanesthetized and unrestrained cats. These data are discussed in terms of an hypothesis which accounts for both the rate of spontaneous activity of serotonergic neurons and the magnitude of their response to serotonin agonist drugs in terms of autoreceptor density on individual neurons. IS - 2-3 JF - European journal of pharmacology SN - 0014-2999 EP - 278 TI - Raphe neurons: firing rate correlates with size of drug response. VL - 90 SP - 275 KW - 5-meodmt KW - 5ht KW - dorsal KW - lsd KW - raphe AU - Jacobs, BL AU - Heym, J AU - Rasmussen, K PY - 1983/06/03/ UR - http://view.ncbi.nlm.nih.gov/pubmed/6873185 ER -