Molecular biology: Slip sliding on DNA Export

@article{citeulike:5983430, abstract = {Dedicated binding proteins stabilize single-stranded DNA, protecting it from breakage and distortion. Once thought to form inert complexes with DNA, such proteins are now shown to be remarkably mobile. The cell's genetic information is maintained as a double helix of interwoven DNA strands in which the information content (the nucleotide sequence) is tucked away between sheltering sugar–phosphate backbones. Although this stable structure benefits long-term information storage, the two strands of DNA must be unwound to allow DNA replication, genetic recombination and repair.}, author = {George, Nicholas P. and Keck, James L.}, citeulike-article-id = {5983430}, citeulike-linkout-0 = {http://dx.doi.org/10.1038/4611067a}, citeulike-linkout-1 = {http://dx.doi.org/10.1038/4611067a}, day = {21}, doi = {10.1038/4611067a}, issn = {0028-0836}, journal = {Nature}, keywords = {dna, single\_molecule, single\_stranded\_dna, ssb}, month = {October}, number = {7267}, pages = {1067--1068}, posted-at = {2009-10-22 17:29:35}, priority = {2}, publisher = {Nature Publishing Group}, title = {Molecular biology: Slip sliding on DNA}, url = {http://dx.doi.org/10.1038/4611067a}, volume = {461}, year = {2009} }

TY - JOUR ID - citeulike:5983430 L3 - citeulike-article-id:5983430 N2 - Dedicated binding proteins stabilize single-stranded DNA, protecting it from breakage and distortion. Once thought to form inert complexes with DNA, such proteins are now shown to be remarkably mobile. The cell's genetic information is maintained as a double helix of interwoven DNA strands in which the information content (the nucleotide sequence) is tucked away between sheltering sugar–phosphate backbones. Although this stable structure benefits long-term information storage, the two strands of DNA must be unwound to allow DNA replication, genetic recombination and repair. IS - 7267 JF - Nature SN - 0028-0836 EP - 1068 TI - Molecular biology: Slip sliding on DNA PB - Nature Publishing Group VL - 461 SP - 1067 KW - dna KW - single_molecule KW - single_stranded_dna KW - ssb AU - George, Nicholas AU - Keck, James PY - 2009/10/21/ UR - http://dx.doi.org/10.1038/4611067a ER -