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Mitogen activated protein kinases (MAPKs) as regulators of spermatogenesis and spermatozoa functions

by: Tal Almog, Zvi Naor
Molecular and Cellular Endocrinology, Vol. 282, No. 1-2. (30 January 2008), pp. 39-44.


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Spermatogenesis, culminating in the generation of mature motile spermatozoa, is a complex biological process that is regulated by cytokines and hormones of the male reproductive system. Spermatozoa must first undergo a series of biochemical processes termed capacitation, which is followed by acrosome reaction and egg fertilization. Here we review the role of mitogen-activated protein kinases (MAPK) cascades in spermatogenesis and spermatozoa functions.


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