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[Effect of vilon and epithalone on induction and growth of induced bladder neoplasms in rats] Export

Vopr Onkol, Vol. 47, No. 5. (2001), pp. 601-607.

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bladder epitalon epithalon neoplams rats vilon

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Experimental data on the effect of peptides--Vilon (Lys-Glu) and Epitalon (Ala-Glu-Asp-Gly)--on induction of urinary bladder tumors in rats are presented. Treatment with Vilon was followed by a significant fall in tumor incidence in 56% of experimental animals, as compared with 75.5% in control, as well as inhibition of early-onset neoplastic changes in the bladder mucosa. No inhibitory effect of Epitalon was recorded.


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