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	A Mass Spectrometry-based Proteomic Approach for Identification of Serine/Threonine-phosphorylated Proteins by Enrichment with Phospho-specific Antibodies: Identification of a Novel Protein, Frigg, as a Protein Kinase A Substrate [My Copy] Mol Cell Proteomics, Vol. 1, No. 7. (1 July 2002), pp. 517-527. by Mads Gronborg, Troels Z. Kristiansen, Allan Stensballe, et al.Jens S. Andersen, Osamu Ohara, Matthias Mann, Ole N. Jensen, Akhilesh Pandey posted to phosphorylation methods mass_spectrometry by anwazo on 2009-11-16 16:38:19 as
	Divergent Modes of Enzyme Inhibition in a Homologous Structure−Activity Series [My Copy] Journal of Medicinal Chemistry, Vol. 52, No. 16. (27 August 2009), pp. 5005-5008. by Rafaela S. Ferreira, Clifford Bryant, Kenny K. H. Ang, James H. McKerrow, Brian K. Shoichet, Adam R. Renslo posted to aggregation by anwazo on 2009-09-09 11:47:54 as along with 1 person k8jbd
	Measurement of Nanomolar Dissociation Constants by Titration Calorimetry and Thermal Shift Assay - Radicicol Binding to Hsp90 and Ethoxzolamide Binding to CAII. [My Copy] International journal of molecular sciences, Vol. 10, No. 6. (2009), pp. 2662-2680. by Asta Zubrienė, Jurgita Matulienė, Lina Baranauskienė, et al.Jelena Jachno, Jolanta Torresan, Vilma Michailovienė, Piotras Cimmperman, Daumantas Matulis posted to tsa thermal_shift methods kinetics kd_determination by anwazo on 2009-09-09 08:53:06 as
	The use of biophysical methods increases success in obtaining liganded crystal structures. [My Copy] Acta crystallographica. Section D, Biological crystallography, Vol. 63, No. Pt 1. (January 2007), pp. 62-71. by Chun-wa W. Chung posted to thermofluor thermal_shift review biophysical_methods by anwazo on 2009-09-03 09:14:02 as
	Recent advances in surface plasmon resonance based techniques for bioanalysis [My Copy] Analytical and Bioanalytical Chemistry, Vol. 387, No. 5. (1 March 2007), pp. 1831-1840. by K. Phillips, Quan Cheng posted to spr review biacore by anwazo on 2009-09-03 09:05:52 as
	"Affinity-proteomics": direct protein identification from biological material using mass spectrometric epitope mapping [My Copy] Analytical and Bioanalytical Chemistry, Vol. 378, No. 4. (17 February 2004), pp. 1102-1111. by Marcus Macht, Andreas Marquardt, Sören-Oliver Deininger, Eugen Damoc, Markus Kohlmann, Michael Przybylski posted to methods mass_spectrometry epitope_mapping by anwazo on 2009-08-24 15:44:44 as
	Mass Spectrometric Mapping of Protein Epitope Structures of Myocardial Infarct Markers Myoglobin and Troponin T† [My Copy] Biochemistry, Vol. 35, No. 49. (1 January 1996), pp. 15633-15639. by Marcus Macht, Winfried Fiedler, Konrad Kurzinger, Michael Przybylski posted to methods mass_spectrometry epitope_mapping by anwazo on 2009-08-20 12:48:59 as
	MALDI/MS-based epitope mapping of antigens bound to immobilized antibodies. [My Copy] Molecular biotechnology, Vol. 20, No. 1. (1 January 2002), pp. 49-62. by Carol E. Parker, Kenneth B. Tomer posted to methods mass_sp epitope_mapping by anwazo on 2009-08-20 12:32:07 as
	Contributions of mass spectrometry to structural immunology [My Copy] Journal of Mass Spectrometry, Vol. 35, No. 4. (2000), pp. 493-503. by Kevin M. Downard posted to methods mass_spectrometry epitope_mapping by anwazo on 2009-08-20 12:09:53 as
	Epitope mapping by proteolysis of antigen-antibody complexes. [My Copy] Methods in molecular biology (Clifton, N.J.), Vol. 524 (2009), pp. 87-101. by Suraj Dhungana, Jason G. Williams, Michael B. Fessler, Kenneth B. Tomer posted to methods mass_spectrometry epitope_mapping by anwazo on 2009-08-20 11:48:39 as
	Dihydroquinone Ansamycins: Toward Resolving the Conflict between Low in Vitro Affinity and High Cellular Potency of Geldanamycin Derivatives [My Copy] Biochemistry, Vol. 45, No. 17. (1 May 2006), pp. 5678-5685. by Anna C. Maroney, Juan J. Marugan, Tara M. Mezzasalma, et al.Alexander N. Barnakov, Thomas A. Garrabrant, Larry E. Weaner, William J. Jones, Ludmila A. Barnakova, Holly K. Koblish, Matthew J. Todd, John A. Masucci, Ingrid C. Deckman, Robert A. Galemmo, Dana L. Johnson posted to thermal_shift ass by anwazo on 2009-08-13 13:12:15 as along with 1 person linagu
	Evaluation of fluorescence-based thermal shift assays for hit identification in drug discovery. [My Copy] Analytical biochemistry, Vol. 332, No. 1. (1 September 2004), pp. 153-159. by Mei-Chu C. Lo, Ann Aulabaugh, Guixian Jin, et al.Rebecca Cowling, Jonathan Bard, Michael Malamas, George Ellestad posted to thermofluor by anwazo on 2009-08-13 12:46:46 as along with 1 person ubcg08l
	Biochemical mechanisms of drug action: what does it take for success? [My Copy] Nat Rev Drug Discov, Vol. 3, No. 9. (September 2004), pp. 801-808. by David C. Swinney posted to review mechanisms kinetics drug_design by anwazo on 2009-08-12 11:10:41 as
	CRYSTALP2: sequence-based protein crystallization propensity prediction [My Copy] BMC Structural Biology, Vol. 9, No. 1. (31 July 2009), 50. by Lukasz Kurgan, Ali Razib, Sara Aghakhani, Scott Dick, Marcin Mizianty, Samad Jahandideh posted to crystallization methods software by anwazo on 2009-08-05 10:46:18 as
	Coding-sequence determinants of gene expression in Escherichia coli. [My Copy] Science (New York, N.Y.), Vol. 324, No. 5924. (10 April 2009), pp. 255-258. by Grzegorz Kudla, Andrew W. Murray, David Tollervey, Joshua B. Plotkin posted to codon_optimization expression expression_systems by anwazo on 2009-04-29 10:02:28 as along with 34 people and 1 group pmalkus codonusage balabu yyfwuhan dbikard kinestetika samgj dswan bpcusack emptyhb sameersoi dpsuslo8 Vincent_Rouilly kintoki erel10 michaelbarton fenghezi VGreiff ramanuja austin twatanab coela polivares rpatward lizbiogen jdbowes operon jasontsai absterga jbhiatt jjray kshundyak zwang friendpine BergmanLab
	Improving the hit-to-lead process: data-driven assessment of drug-like and lead-like screening hits. [My Copy] Drug Discov Today, Vol. 11, No. 3-4. (February 2006), pp. 175-180. by T. Wunberg, M. Hendrix, A. Hillisch, et al.M. Lobell, H. Meier, C. Schmeck, H. Wild, B. Hinzen posted to bayer hit-to-lead leads methods review target_identification target_validation by anwazo on 2009-04-16 09:40:59 as along with 3 people jbesnard Yanno nicklynch
	Off-Target Decoding of a Multitarget Kinase Inhibitor by Chemical Proteomics [My Copy] ChemBioChem, Vol. 9999, No. 9999. (2009), NA. by Enrico Missner, Inke Bahr, Volker Badock, Ulrich Lücking, Gerhard Siemeister, Peter Donner posted to chemical_proteomics mass_spectrometry methods small-molecule-protein-interaction by anwazo on 2009-04-09 14:35:00 as along with 1 person Yanno
	Understanding the physical properties that control protein crystallization by analysis of large-scale experimental data. [My Copy] Nature biotechnology (14 December 2008) by W Nicholson N. Price Ii, Yang Chen, Samuel K K. Handelman, et al.Helen Neely, Philip Manor, Richard Karlin, Rajesh Nair, Jinfeng Liu, Michael Baran, John Everett, Saichiu N N. Tong, Farhad Forouhar, Swarup S S. Swaminathan, Thomas Acton, Rong Xiao, Joseph R R. Luft, Angela Lauricella, George T T. Detitta, Burkhard Rost, Gaetano T T. Montelione, John F F. Hunt posted to crystallization review thermal_shift thermofluor by anwazo on 2009-04-09 09:20:49 as along with 5 people betainverse kevinchannon allysonlister egonw neils
	Current strategies for the use of affinity tags and tag removal for the purification of recombinant proteins [My Copy] Protein Expression and Purification, Vol. 48, No. 1. (July 2006), pp. 1-13. by José Arnau, Conni Lauritzen, Gitte E. Petersen, John Pedersen posted to affinity his-tag tagzyme unizyme by anwazo on 2009-04-08 14:15:07 as along with 3 people taenneken barneb guhjy
	Ligand-induced global transitions in the catalytic domain of protein kinase A [My Copy] Proceedings of the National Academy of Sciences, Vol. 106, No. 9. (3 March 2009), pp. 3023-3028. by Changbong Hyeon, Patricia A. Jennings, Joseph A. Adams, JosÃ© N. Onuchic posted to allosteric cracking kinetics by anwazo on 2009-04-08 11:16:01 as along with 1 person and 1 group sobolevnrm baker-group
	Exact and user-friendly kinetic analysis of the two-step rapid equilibrium Michaelis–Menten mechanism [My Copy] Analytical Biochemistry, Vol. 387, No. 2. (15 April 2009), pp. 276-279. by Sylvie Garneau-Tsodikova, Irina A. Shkel, Oleg V. Tsodikov posted to kinetics by anwazo on 2009-03-17 09:10:59 as
	Activation loop phosphorylation and catalysis in protein kinases: is there functional evidence for the autoinhibitor model? [My Copy] Biochemistry, Vol. 42, No. 3. (28 January 2003), pp. 601-607. by J. A. Adams posted to autoinhibition phosphorylation review by anwazo on 2009-03-12 14:26:47 as along with 1 person tjimenez
	Kinetic mechanism of fully activated S6K1 protein kinase. [My Copy] The Journal of biological chemistry, Vol. 283, No. 18. (2 May 2008), pp. 11972-11980. by Malik M. Keshwani, Thomas K. Harris posted to kinetics mechanisms s6k1 by anwazo on 2009-03-12 13:47:24 as along with 1 person guhjy
	Phosphoryl Transfer Step in the C-terminal Src Kinase Controls Src Recognition [My Copy] J. Biol. Chem., Vol. 280, No. 9. (4 March 2005), pp. 7769-7776. by Scot A. Lieser, Caitlin Shindler, Brandon E. Aubol, Sungsoo Lee, Gongqin Sun, Joseph A. Adams posted to kinetics phosphorylation src by anwazo on 2009-03-12 13:16:31 as
	Small-molecule microarrays as tools in ligand discovery [My Copy] Chem. Soc. Rev., Vol. 37, No. 7. (2008), pp. 1385-1394. by Arturo J. Vegas, Jason H. Fuller, Angela N. Koehler posted to microarrays review small-molecule-protein-interaction by anwazo on 2009-03-09 09:22:29 as
	Informed use of proteolytic inhibitors in biomarker discovery [My Copy] Rapid Communications in Mass Spectrometry, Vol. 18, No. 9. (2004), pp. 1001-1002. by Robert, Michael G. Klug, Mark E. Bolander, David C. Muddiman posted to mass_difference mass_spectrometry protease_inhibitors by anwazo on 2009-03-04 16:47:11 as
	Towards a ‘universal’ nucleant for protein crystallization [My Copy] Trends in Biotechnology (26 December 2008) by E. Saridakis, N. Chayen posted to crystallization methods nucleation review by anwazo on 2009-01-08 13:32:56 as
	Calculating reaction rate constants and estimating the efficacy of selective enzyme inhibitors [My Copy] Analytical Biochemistry, Vol. 383, No. 2. (15 December 2008), pp. 323-325. by H. Eikemo, T. Skomedal, F. Levy, J. Osnes posted to kinetics methods rate_constants by anwazo on 2008-11-21 09:56:44 as
	Previsible silver staining of protein in electrophoresis gels with mass spectrometry compatibility. [My Copy] Analytical biochemistry, Vol. 383, No. 2. (15 December 2008), pp. 137-143. by L. T. Jin, X. K. Li, W. T. Cong, S. Y. Hwang, J. K. Choi posted to mass_spectrometry methods protein_stains staining by anwazo on 2008-11-21 09:54:21 as along with 1 person guhjy
	Death-associated protein kinase phosphorylates ZIP kinase, forming a unique kinase hierarchy to activate its cell death functions. [My Copy] Molecular and cellular biology, Vol. 24, No. 19. (October 2004), pp. 8611-8626. by G. Shani, L. Marash, D. Gozuacik, et al.S. Bialik, L. Teitelbaum, G. Shohat, A. Kimchi posted to dapk3 leucine_zipper oligomerization by anwazo on 2008-11-12 15:42:25 as
	ZIP kinase, a novel serine/threonine kinase which mediates apoptosis. [My Copy] Molecular and cellular biology, Vol. 18, No. 3. (March 1998), pp. 1642-1651. by T. Kawai, M. Matsumoto, K. Takeda, H. Sanjo, S. Akira posted to oligomerization phosphorylation zipk by anwazo on 2008-11-12 15:14:13 as
	Regulation of Zipper-interacting Protein Kinase Activity in Vitro and in Vivo by Multisite Phosphorylation [My Copy] J. Biol. Chem., Vol. 280, No. 10. (11 March 2005), pp. 9363-9374. by Paul R. Graves, Karen M. Winkfield, Timothy A. Haystead posted to leucine_zipper oligomerization zipk by anwazo on 2008-11-12 15:10:47 as
	Activation segment dimerization: a mechanism for kinase autophosphorylation of non-consensus sites [My Copy] The EMBO Journal, Vol. aop, No. current. (31 January 2008) by Ashley C. W. Pike, Peter Rellos, Frank H. Niesen, et al.Andrew Turnbull, Antony W. Oliver, Sirlester A. Parker, Benjamin E. Turk, Laurence H. Pearl, Stefan Knapp posted to activation_loop autophosphorylation structural_research by anwazo on 2008-11-12 09:33:23 as along with 1 person neils
	Production of selenomethionyl-derivatized proteins in baculovirus-infected insect cells [My Copy] Protein Sci, Vol. 16, No. 9. (1 September 2007), pp. 2023-2029. by Ciaran N. Cronin, Kheng B. Lim, Joe Rogers posted to baculo methods semet by anwazo on 2008-11-07 12:41:17 as
	Top-Down Identification and Characterization of Biomolecules by Mass Spectrometry [My Copy] Journal of the American Society for Mass Spectrometry, Vol. 19, No. 8. (August 2008), pp. 1045-1053. by K. Breuker, M. Jin, X. Han, H. Jiang, F. Mclafferty posted to mass_spectrometry by anwazo on 2008-10-29 13:13:55 as along with 1 person guhjy
	Solution Structures of UBA Domains Reveal a Conserved Hydrophobic Surface for Protein–Protein Interactions [My Copy] Journal of Molecular Biology, Vol. 319, No. 5. (21 June 2002), pp. 1243-1255. by T. Mueller, J. Feigon posted to domain uba by anwazo on 2008-10-23 16:25:30 as
	Protein crystallization by rational mutagenesis of surface residues: Lys to Ala mutations promote crystallization of RhoGDI [My Copy] Acta Crystallographica Section D, Vol. 57, No. 5. (May 2001), pp. 679-688. by Kenton L. Longenecker, Sarah M. Garrard, Peter J. Sheffield, Zygmunt S. Derewenda posted to crystallization mutagenesis ser surface_entropy_reduction by anwazo on 2008-09-19 11:47:13 as
	Novel buffer systems for macromolecular crystallization. [My Copy] Acta Crystallogr D Biol Crystallogr, Vol. 60, No. Pt 3. (March 2004), pp. 610-612. by J. Newman posted to buffer crystallization methods screening by anwazo on 2008-09-18 15:20:04 as along with 2 people and 2 groups Rayn jwm Radiation_Damage Stressosome
	Crystallization Optimum Solubility Screening: using crystallization results to identify the optimal buffer for protein crystal formation [My Copy] Acta Crystallographica Section F: Structural Biology and Crystallization Communications, Vol. 61, No. 12. (December 2005), pp. 1035-1038. by B. Collins, R. C. Stevens, R. Page posted to crystallization methods screening by anwazo on 2008-09-18 15:12:09 as
	Nmr in drug discovery [My Copy] Nat Rev Drug Discov, Vol. 1, No. 3. (March 2002), pp. 211-219. by Maurizio Pellecchia, Daniel S. Sem, Kurt Wuthrich posted to nmr review by anwazo on 2008-09-12 13:45:23 as along with 1 person majacassidy
	An approach to quality management in structural biology: Biophysical selection of proteins for successful crystallization [My Copy] Journal of Structural Biology, Vol. 162, No. 3. (June 2008), pp. 451-459. by Frank H. Niesen, Anja Koch, Ulf Lenski, et al.Ulrich Harttig, Yvette Roske, Udo Heinemann, Klaus P. Hofmann posted to biophysics calorimetry crystallization dls dsc fold ftir genomics methods structural_research by anwazo on 2008-09-11 13:26:35 as
	Parallel kinetic analysis and affinity determination of hundreds of monoclonal antibodies using the ProteOn XPR36 [My Copy] Analytical Biochemistry, Vol. In Press, Uncorrected Proof by Oded Nahshol, Vered Bronner, Ariel Notcovich, Laetitia Rubrecht, Daniel Laune, Tsafrir Bravman posted to antibodies biacore biorad proteon spr by anwazo on 2008-09-10 12:10:42 as
	Thermodynamic characterization of pyrazole and azaindole derivatives binding to p38 mitogen-activated protein kinase using Biacore T100 technology and van't Hoff analysis [My Copy] Analytical Biochemistry, Vol. In Press, Uncorrected Proof by Giuseppe A. Papalia, Anthony M. Giannetti, Nidhi Arora, David G. Myszka posted to biacore p38 thermodynamics vant_hoff by anwazo on 2008-09-10 11:41:37 as
	Is proteomics the new genomics? [My Copy] Cell, Vol. 130, No. 3. (10 August 2007), pp. 395-398. by Jürgen Cox, Matthias Mann posted to mass_spectrometry proteomics review by anwazo on 2008-08-25 09:35:38 as along with 7 people pekrau yylin frohike grahamc fishtank oelemento Pao-Yang
	Demonstration of a Genetic Therapeutic Index for Tumors Expressing Oncogenic BRAF by the Kinase Inhibitor SB-590885 [My Copy] Cancer Res, Vol. 66, No. 23. (1 December 2006), pp. 11100-11105. by Alastair J. King, Denis R. Patrick, Roberta S. Batorsky, et al.Maureen L. Ho, Hieu T. Do, Shu Y. Zhang, Rakesh Kumar, David W. Rusnak, Andrew K. Takle, David M. Wilson, Erin Hugger, Lifu Wang, Florian Karreth, Julie C. Lougheed, Jae Lee, David Chau, Thomas J. Stout, Earl W. May, Cynthia M. Rominger, Michael D. Schaber, Lusong Luo, Ami S. Lakdawala, Jerry L. Adams, Rooja G. Contractor, Keiran S. Smalley, Meenhard Herlyn, Michael M. Morrissey, David A. Tuveson, Pearl S. Huang posted to braf gsk sb-590885 structure by anwazo on 2007-08-24 12:02:35 as
	Making soluble recombinant proteins from Escherichia coli: Lessons learned from the human interferon alpha [My Copy] Journal of Biotechnology In ECB13, 13th European Congress on Biotechnology, Vol. 131, No. 2, Supplement 1. (September 2007), S71. by Imen Rabhi-Essafi, Noureddine Khalaf, Amine Sadok, Dahmani M. Fathallah posted to expression expression_ecoli interferon by anwazo on 2007-08-23 13:30:18 as
	Regulation of Xenopus Aurora A activation by TPX2. [My Copy] J Biol Chem, Vol. 279, No. 10. (5 March 2004), pp. 9008-9015. by P. A. Eyers, J. L. Maller posted to aurora review tpx2 by anwazo on 2007-08-23 11:22:27 as
	Binding of TPX2 to Aurora A Alters Substrate and Inhibitor Interactions. [My Copy] Biochemistry (18 August 2007) by Kelly Anderson, Jingsong Yang, Kristin Koretke, et al.Kelvin Nurse, Amy Calamari, Robert B. Kirkpatrick, Denis Patrick, Domingos Silva, Peter J. Tummino, Robert A. Copeland, Zhihong Lai posted to aurora sar structure tpx2 vx-680 by anwazo on 2007-08-23 11:21:06 as
	The Activation and Inhibition of Cyclin-Dependent Kinase-5 by Phosphorylation [My Copy] Biochemistry (22 August 2007) by B. Zhang, V. B. C. Tan, K. M. Lim, T. E. Tay posted to cdk phosphorylation by anwazo on 2007-08-23 10:29:52 as
	Structural Evolution of the Protein Kinase-Like Superfamily. [My Copy] PLoS Comput Biol, Vol. 1, No. 5. (21 October 2005) by Eric D D. Scheeff, Philip E E. Bourne posted to kinase review structure by anwazo on 2007-08-23 09:55:51 as along with 4 people and 2 groups yuslinaz BragilMassoud ana renatomilani structural_bioinformatics Bioinformatics

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methods	24
review	22
mass_spectrometry	12
crystallization	9
structure	8
proteomics	8
kinetics	7
phosphorylation	7
cancer	7
inhibitor	7
braf	6
structural_research	6
expression	6
signaling	5
protein	5
epitope_mapping	5
immobilized	4
thermal_shift	4
noref	4
domain	3
aurora	3
mtor	3
kinase	3
oligomerization	3
thermofluor	3
purification	3
biacore	3
target_identification	3
high-throughput	3
cdk	2
databases	2
leucine_zipper	2
zipk	2
baculo	2
mechanisms	2
p38	2
assay	2
pi3k	2
reductive_methylation	2
microarrays	2
small-molecule-protein-interaction	2
screening	2
tpx2	2
target_validation	2
hedgehog	2
sar	2
protease_inhibitors	2
spr	2
cloning	2
chemical	2
bioinformatics	2
leads	1
antibodies	1
stability	1
allosteric	1
dls	1
mab	1
vegfr2	1
protein_stains	1
proteon	1
tags	1
buffer	1
staining	1
bayer	1
dapk3	1
interferon	1
chemical_proteomics	1
e64	1
uba	1
codon_optimization	1
cpd	1
nucleation	1
his-tag	1
dsc	1
x-ray	1
ser	1
expression_mammalian	1
limited_proteolysis	1
fold	1
genomics	1
software	1
kd_determination	1
cho	1
kif14	1
sh2	1
nmr	1
p85	1
atpase	1
biophysics	1
mass_difference	1
autophosphorylation	1
ftir	1
carboxyl_protease	1
gsk	1
monoclonal	1
ass	1
biorad	1
activation_loop	1
semet	1
mass_sp	1
vant_hoff	1
hit-to-lead	1
unizyme	1
tagzyme	1
angiogenesis	1
calorimetry	1
nuclease	1
formulation	1
thermodynamics	1
rate_constants	1
autoinhibition	1
mutation	1
expression_systems	1
expression_ecoli	1
cracking	1
aggregation	1
surface_entropy_reduction	1
src	1
affinity	1
tsa	1
recombinant	1
cystein_protease	1
fluorescence	1
pdk1	1
sb-590885	1
vx-680	1
mutagenesis	1
protein_protein_interaction	1
s6k1	1
drug_design	1
biophysical_methods	1

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