An iterative method for extracting energy-like quantities from protein structures. Export

@article{citeulike:3749718, abstract = {We present a method (ENERGI) for extracting energy-like quantities from a data base of protein structures. In this paper, we use the method to generate pairwise additive amino acid "energy" scores. These scores are obtained by iteration until they correctly discriminate a set of known protein folds from decoy conformations. The method succeeds in lattice model tests and in the gapless threading problem as defined by Maiorov and Crippen [Maiorov, V. N. \& Crippen, G. M. (1992) J. Mol. Biol. 227, 876-888]. A more challenging test of threading a larger set of test proteins derived from the representative set of Hobohm and Sander [Hobohm, U. \& Sander, C. (1994) Protein Sci. 3, 522-524] is used as a "workbench" for exploring how the ENERGI scores depend on their parameter sets.}, author = {Thomas, P. D. and Dill, K. A.}, citeulike-article-id = {3749718}, citeulike-linkout-0 = {http://view.ncbi.nlm.nih.gov/pubmed/8876187}, citeulike-linkout-1 = {http://www.hubmed.org/display.cgi?uids=8876187}, day = {15}, issn = {0027-8424}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, keywords = {classification}, month = {October}, number = {21}, pages = {11628--11633}, posted-at = {2008-12-05 09:43:57}, priority = {2}, title = {An iterative method for extracting energy-like quantities from protein structures.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/8876187}, volume = {93}, year = {1996} }

TY - JOUR ID - citeulike:3749718 L3 - citeulike-article-id:3749718 N2 - We present a method (ENERGI) for extracting energy-like quantities from a data base of protein structures. In this paper, we use the method to generate pairwise additive amino acid "energy" scores. These scores are obtained by iteration until they correctly discriminate a set of known protein folds from decoy conformations. The method succeeds in lattice model tests and in the gapless threading problem as defined by Maiorov and Crippen [Maiorov, V. N. & Crippen, G. M. (1992) J. Mol. Biol. 227, 876-888]. A more challenging test of threading a larger set of test proteins derived from the representative set of Hobohm and Sander [Hobohm, U. & Sander, C. (1994) Protein Sci. 3, 522-524] is used as a "workbench" for exploring how the ENERGI scores depend on their parameter sets. IS - 21 JF - Proceedings of the National Academy of Sciences of the United States of America SN - 0027-8424 EP - 11633 TI - An iterative method for extracting energy-like quantities from protein structures. VL - 93 SP - 11628 KW - classification AU - Thomas, PD AU - Dill, KA PY - 1996/10/15/ UR - http://view.ncbi.nlm.nih.gov/pubmed/8876187 ER -