Evaluation and characterization of generalized anxiety and depression in patients with primary brain tumors. Export

@article{citeulike:2468624, abstract = {To determine clinical and sociodemographic factors that are associated with major neuropsychiatric illnesses among brain tumor patients, we administered a modified version of the Brief Patient Health Questionnaire and a demographic data form to 363 adult neuro-oncology patients. Responses were analyzed to assess for associations between demographic variables, clinical variables, and symptoms consistent with diagnoses of generalized anxiety disorder and/or depression. Multivariate logistic regression analyses showed that female gender was associated with the presence of symptoms of anxiety, depression, and combined anxiety and depression. Lower WHO tumor grade classifications, lower education level, and a history of psychiatric illness also emerged as important predictors of symptoms consistent with anxiety and/or depression. Marital status and presence of past/current medical illness trended toward being significantly associated with depression alone. Patient use of psychiatric medication was not associated with any study variables. Results of the present study suggest several hypotheses to test with neuro-oncology patients in further longitudinal analyses, which would benefit from the inclusion of a wider range of neuropsychiatric symptoms in conjunction with neurocognitive and functional impairment variables.}, address = {Tug McGraw Center for Quality of Life/Supportive Care Research, Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, NC, USA.}, author = {Arnold, Staci D D. and Forman, Leslie M M. and Brigidi, Bart D D. and Carter, Karen E E. and Schweitzer, Holly A A. and Quinn, Heather E E. and Guill, A Bebe B. and Herndon Ii, James E E. and Raynor, Renee H H.}, citeulike-article-id = {2468624}, citeulike-linkout-0 = {http://dx.doi.org/10.1215/15228517-2007-057}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/18314416}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=18314416}, day = {26}, doi = {10.1215/15228517-2007-057}, issn = {1522-8517}, journal = {Neuro Oncol}, keywords = {anxiety, brain\_tumors, depression}, month = {February}, posted-at = {2008-03-05 02:03:15}, priority = {3}, title = {Evaluation and characterization of generalized anxiety and depression in patients with primary brain tumors.}, url = {http://dx.doi.org/10.1215/15228517-2007-057}, year = {2008} }

TY - JOUR ID - citeulike:2468624 L3 - citeulike-article-id:2468624 N2 - To determine clinical and sociodemographic factors that are associated with major neuropsychiatric illnesses among brain tumor patients, we administered a modified version of the Brief Patient Health Questionnaire and a demographic data form to 363 adult neuro-oncology patients. Responses were analyzed to assess for associations between demographic variables, clinical variables, and symptoms consistent with diagnoses of generalized anxiety disorder and/or depression. Multivariate logistic regression analyses showed that female gender was associated with the presence of symptoms of anxiety, depression, and combined anxiety and depression. Lower WHO tumor grade classifications, lower education level, and a history of psychiatric illness also emerged as important predictors of symptoms consistent with anxiety and/or depression. Marital status and presence of past/current medical illness trended toward being significantly associated with depression alone. Patient use of psychiatric medication was not associated with any study variables. Results of the present study suggest several hypotheses to test with neuro-oncology patients in further longitudinal analyses, which would benefit from the inclusion of a wider range of neuropsychiatric symptoms in conjunction with neurocognitive and functional impairment variables. JF - Neuro Oncol SN - 1522-8517 AD - Tug McGraw Center for Quality of Life/Supportive Care Research, Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, NC, USA. TI - Evaluation and characterization of generalized anxiety and depression in patients with primary brain tumors. KW - anxiety KW - brain_tumors KW - depression AU - Arnold, Staci D AU - Forman, Leslie M AU - Brigidi, Bart D AU - Carter, Karen E AU - Schweitzer, Holly A AU - Quinn, Heather E AU - Guill, A Bebe AU - Herndon Ii, James E AU - Raynor, Renee H PY - 2008/02/26/ UR - http://dx.doi.org/10.1215/15228517-2007-057 ER -