Homonymous field defect as the first manifestation of Creutzfeldt-Jakob disease. Export

@article{citeulike:3203817, abstract = {PURPOSE: Although in the early stage of Creutzfeldt-Jakob disease most patients have obvious dementia, we found that the disease can be diagnosed in patients solely on the basis of a visual system disorder. METHODS: We examined three patients who initially complained of a nonspecific, insidious visual disturbance. RESULTS: The three patients were found to have Creutzfeldt-Jakob disease, confirmed by histopathologic analysis. Each patient had a homonymous hemianopsia on the first neuro-ophthalmologic examination. The initial neurologic, neuroimaging, and electrophysiologic examinations were not conclusive. The subsequent rapid deterioration in the neurologic status, including dementia and typical electroencephalographic changes, was suggestive of Creutzfeldt-Jakob disease. CONCLUSION: At onset of Creutzfeldt-Jakob disease, patients may have a homonymous hemianopsia despite normal results of magnetic resonance imaging of the brain and neurologic examination.}, address = {Department of Ophthalmology, New York University Medical Center, New York, USA.}, author = {Vargas, M. E. and Kupersmith, M. J. and Savino, P. J. and Petito, F. and Frohman, L. P. and Warren, F. A.}, citeulike-article-id = {3203817}, citeulike-linkout-0 = {http://view.ncbi.nlm.nih.gov/pubmed/7709975}, citeulike-linkout-1 = {http://www.hubmed.org/display.cgi?uids=7709975}, issn = {0002-9394}, journal = {American journal of ophthalmology}, keywords = {cjd, heidenhain, phenotype, prion}, month = {April}, number = {4}, pages = {497--504}, posted-at = {2008-09-08 02:48:07}, priority = {0}, title = {Homonymous field defect as the first manifestation of Creutzfeldt-Jakob disease.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/7709975}, volume = {119}, year = {1995} }

TY - JOUR ID - citeulike:3203817 L3 - citeulike-article-id:3203817 N2 - PURPOSE: Although in the early stage of Creutzfeldt-Jakob disease most patients have obvious dementia, we found that the disease can be diagnosed in patients solely on the basis of a visual system disorder. METHODS: We examined three patients who initially complained of a nonspecific, insidious visual disturbance. RESULTS: The three patients were found to have Creutzfeldt-Jakob disease, confirmed by histopathologic analysis. Each patient had a homonymous hemianopsia on the first neuro-ophthalmologic examination. The initial neurologic, neuroimaging, and electrophysiologic examinations were not conclusive. The subsequent rapid deterioration in the neurologic status, including dementia and typical electroencephalographic changes, was suggestive of Creutzfeldt-Jakob disease. CONCLUSION: At onset of Creutzfeldt-Jakob disease, patients may have a homonymous hemianopsia despite normal results of magnetic resonance imaging of the brain and neurologic examination. IS - 4 JF - American journal of ophthalmology SN - 0002-9394 AD - Department of Ophthalmology, New York University Medical Center, New York, USA. EP - 504 TI - Homonymous field defect as the first manifestation of Creutzfeldt-Jakob disease. VL - 119 SP - 497 KW - cjd KW - heidenhain KW - phenotype KW - prion AU - Vargas, ME AU - Kupersmith, MJ AU - Savino, PJ AU - Petito, F AU - Frohman, LP AU - Warren, FA PY - 1995/04// UR - http://view.ncbi.nlm.nih.gov/pubmed/7709975 ER -