Pre-mRNA processing reaches back to transcription and ahead to translation. Export

@article{citeulike:4155006, abstract = {The pathway from gene activation in the nucleus to mRNA translation and decay at specific locations in the cytoplasm is both streamlined and highly interconnected. This review discusses how pre-mRNA processing, including 5' cap addition, splicing, and polyadenylation, contributes to both the efficiency and fidelity of gene expression. The connections of pre-mRNA processing to upstream events in transcription and downstream events, including translation and mRNA decay, are elaborate, extensive, and remarkably interwoven.}, author = {Moore, M. J. and Proudfoot, N. J.}, citeulike-article-id = {4155006}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.cell.2009.02.001}, citeulike-linkout-1 = {http://linkinghub.elsevier.com/retrieve/pii/S0092867409001330}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/19239889}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=19239889}, day = {20}, doi = {10.1016/j.cell.2009.02.001}, issn = {1097-4172}, journal = {Cell}, keywords = {polyadenylation, rna, splicing, transcription, translation}, month = {February}, number = {4}, pages = {688--700}, posted-at = {2009-11-05 15:04:36}, priority = {2}, title = {Pre-mRNA processing reaches back to transcription and ahead to translation.}, url = {http://dx.doi.org/10.1016/j.cell.2009.02.001}, volume = {136}, year = {2009} }

TY - JOUR ID - citeulike:4155006 L3 - citeulike-article-id:4155006 N2 - The pathway from gene activation in the nucleus to mRNA translation and decay at specific locations in the cytoplasm is both streamlined and highly interconnected. This review discusses how pre-mRNA processing, including 5' cap addition, splicing, and polyadenylation, contributes to both the efficiency and fidelity of gene expression. The connections of pre-mRNA processing to upstream events in transcription and downstream events, including translation and mRNA decay, are elaborate, extensive, and remarkably interwoven. IS - 4 JF - Cell SN - 1097-4172 EP - 700 TI - Pre-mRNA processing reaches back to transcription and ahead to translation. VL - 136 SP - 688 KW - polyadenylation KW - rna KW - splicing KW - transcription KW - translation AU - Moore, MJ AU - Proudfoot, NJ PY - 2009/02/20/ UR - http://dx.doi.org/10.1016/j.cell.2009.02.001 ER -