Three-dimensional methods for quantification of cancellous bone architecture Export

@article{RefWorks:9700, abstract = {Recent development in three-dimensional (3-D) imaging of cancellous bone has made possible true 3-D quantification of trabecular architecture, This provides a significant improvement of the tools available for studying and understanding the mechanical functions of cancellous bone, This article reviews the different techniques for 3-D imaging, which include serial sectioning, X-ray tomographic methods, and NMR scanning, Basic architectural features of cancellous bone are discussed, and it is argued that connectivity and architectural anisotropy (fabric) are of special interest in mechanics- architecture relations, A full characterization of elastic mechanical properties is, with traditional mechanical testing, virtually impossible, but 3-D reconstruction in combination with newly developed methods for large-scale finite element analysis allow calculations of all elastic properties at the cancellous bone continuum level, Connectivity has traditionally been approached by various 2-D methods, but none of these methods have any known relation to 3-D connectivity, A topological approach allows unbiased quantification of connectivity, and this further allows expressions of the mean size of individual trabeculae, which has previously also been approached by a number of uncertain 2-D methods. Anisotropy may be quantified by fundamentally different methods, The well- known mean intercept length method is an interface-based method, whereas the volume orientation method is representative of volume based methods. Recent studies indicate that volume- based methods are at least as good as interface-based methods in predicting mechanical anisotropy, Any other architectural property may be quantified from 3-D reconstructions of cancellous bone specimens as long as an explicit definition of the property can be given, This challenges intuitive and vaguely defined architectural properties and forces bone scientists toward 3-D thinking. (C) 1997 by Elsevier Science Inc}, author = {Odgaard, A.}, citeulike-article-id = {2375249}, comment = {ID: 33; Journal English Review ELSEVIER SCIENCE INC 37 APR WT610 NEW YORK Odgaard A AARHUS UNIV HOSP,ORTHOPAED RES LAB,DEPT ORTHOPAED SURG,BYGNING 1A,DK-8000 AARHUS C,DENMARK BONE 655 AVENUE OF THE AMERICAS, NEW YORK, NY 10010; RP: IN FILE}, journal = {Bone}, keywords = {3d, age-related-changes, anisotropy, bone, compression, epiphysis, fracture, histomorphometry, in-refman, method-paper, orientation, quantification, reconstruction, spine, tibia, trabecular}, number = {4}, pages = {315--328}, posted-at = {2008-02-14 16:06:19}, priority = {0}, title = {Three-dimensional methods for quantification of cancellous bone architecture}, volume = {20}, year = {1997} }

TY - JOUR ID - RefWorks:9700 L3 - citeulike-article-id:2375249 N2 - Recent development in three-dimensional (3-D) imaging of cancellous bone has made possible true 3-D quantification of trabecular architecture, This provides a significant improvement of the tools available for studying and understanding the mechanical functions of cancellous bone, This article reviews the different techniques for 3-D imaging, which include serial sectioning, X-ray tomographic methods, and NMR scanning, Basic architectural features of cancellous bone are discussed, and it is argued that connectivity and architectural anisotropy (fabric) are of special interest in mechanics- architecture relations, A full characterization of elastic mechanical properties is, with traditional mechanical testing, virtually impossible, but 3-D reconstruction in combination with newly developed methods for large-scale finite element analysis allow calculations of all elastic properties at the cancellous bone continuum level, Connectivity has traditionally been approached by various 2-D methods, but none of these methods have any known relation to 3-D connectivity, A topological approach allows unbiased quantification of connectivity, and this further allows expressions of the mean size of individual trabeculae, which has previously also been approached by a number of uncertain 2-D methods. Anisotropy may be quantified by fundamentally different methods, The well- known mean intercept length method is an interface-based method, whereas the volume orientation method is representative of volume based methods. Recent studies indicate that volume- based methods are at least as good as interface-based methods in predicting mechanical anisotropy, Any other architectural property may be quantified from 3-D reconstructions of cancellous bone specimens as long as an explicit definition of the property can be given, This challenges intuitive and vaguely defined architectural properties and forces bone scientists toward 3-D thinking. (C) 1997 by Elsevier Science Inc IS - 4 JF - Bone EP - 328 TI - Three-dimensional methods for quantification of cancellous bone architecture VL - 20 SP - 315 KW - 3d KW - age-related-changes KW - anisotropy KW - bone KW - compression KW - epiphysis KW - fracture KW - histomorphometry KW - in-refman KW - method-paper KW - orientation KW - quantification KW - reconstruction KW - spine KW - tibia KW - trabecular N1 - ID: 33; Journal English Review ELSEVIER SCIENCE INC 37 APR WT610 NEW YORK Odgaard A AARHUS UNIV HOSP,ORTHOPAED RES LAB,DEPT ORTHOPAED SURG,BYGNING 1A,DK-8000 AARHUS C,DENMARK BONE 655 AVENUE OF THE AMERICAS, NEW YORK, NY 10010; RP: IN FILE AU - Odgaard, A PY - 1997/// ER -