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Beckwith-Wiedemann syndrome.

by: Rosanna Weksberg, Cheryl Shuman, J. Bruce Beckwith
European journal of human genetics : EJHG, Vol. 18, No. 1. (24 January 2010), pp. 8-14, doi:10.1038/ejhg.2009.106  Key: citeulike:4950398

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Abstract

Beckwith-Wiedemann syndrome (BWS) is a model disorder for the study of imprinting, growth dysregulation, and tumorigenesis. Unique observations in this disorder point to an important embryonic developmental window relevant to the observations of increased monozygotic twinning and an increased rate of epigenetic errors after subfertility/assisted reproduction.


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