Steady-State Measurements on the Fructose 6-Phosphate/Fructose 1,6-Bisphosphate Interconversion Cycle Export

@article{citeulike:2407065, abstract = {Abstract: Steady-state measurements are presented of the concentration of fructose 1,6-bisphosphate (F16BP) in a flow reactor containing the enzymes phosphofructokinase 1, fructose 1,6-bisphosphatase, and creatine kinase, under the regulation of combinations of the regulatory species fructose 2,6-bisphosphate, citrate, glycerol 3-phosphate, and adenosine 5'-monophosphate. We use a recently described capillary electrophoresis protocol for sample analysis, which allows for the simultaneous separation and quantification of many glycolytic species, including isomers. We compare our results to theoretical work on logical properties of biological reaction networks and conclude that the fructose 6-phosphate/fructose 1,6-bisphosphate interconversion cycle can be considered to be a switch in glycolysis: a fuzzy logic aggregation operator.}, address = {Department of Chemistry, Stanford University, Stanford, California 94305}, author = {Hauri, D. C. and Shen, P. and Arkin, A. P. and Ross, J.}, citeulike-article-id = {2407065}, citeulike-linkout-0 = {http://dx.doi.org/10.1021/jp962901t}, citeulike-linkout-1 = {http://pubs.acs.org/doi/abs/10.1021/jp962901t}, day = {8}, doi = {10.1021/jp962901t}, journal = {J. Phys. Chem. B}, keywords = {16bisphosphate, 16diphosphate, 6phosphate, background, fructose, general, steady\_state}, month = {May}, number = {19}, pages = {3872--3876}, posted-at = {2008-02-21 14:24:07}, priority = {2}, title = {Steady-State Measurements on the Fructose 6-Phosphate/Fructose 1,6-Bisphosphate Interconversion Cycle}, url = {http://dx.doi.org/10.1021/jp962901t}, volume = {101}, year = {1997} }

TY - JOUR ID - citeulike:2407065 L3 - citeulike-article-id:2407065 N2 - Abstract: Steady-state measurements are presented of the concentration of fructose 1,6-bisphosphate (F16BP) in a flow reactor containing the enzymes phosphofructokinase 1, fructose 1,6-bisphosphatase, and creatine kinase, under the regulation of combinations of the regulatory species fructose 2,6-bisphosphate, citrate, glycerol 3-phosphate, and adenosine 5'-monophosphate. We use a recently described capillary electrophoresis protocol for sample analysis, which allows for the simultaneous separation and quantification of many glycolytic species, including isomers. We compare our results to theoretical work on logical properties of biological reaction networks and conclude that the fructose 6-phosphate/fructose 1,6-bisphosphate interconversion cycle can be considered to be a switch in glycolysis: a fuzzy logic aggregation operator. IS - 19 JF - J. Phys. Chem. B AD - Department of Chemistry, Stanford University, Stanford, California 94305 EP - 3876 TI - Steady-State Measurements on the Fructose 6-Phosphate/Fructose 1,6-Bisphosphate Interconversion Cycle VL - 101 SP - 3872 KW - 16bisphosphate KW - 16diphosphate KW - 6phosphate KW - background KW - fructose KW - general KW - steady_state AU - Hauri, DC AU - Shen, P AU - Arkin, AP AU - Ross, J PY - 1997/05/08/ UR - http://dx.doi.org/10.1021/jp962901t ER -