Medium scale integration of molecular logic gates in an automaton. Export

@article{citeulike:2940586, abstract = {The assembly of molecular automata that perform increasingly complex tasks, such as game playing, presents an unbiased test of molecular computation. We now report a second-generation deoxyribozyme-based automaton, MAYA-II, which plays a complete game of tic-tac-toe according to a perfect strategy. In silicon terminology, MAYA-II represents the first "medium-scale integrated molecular circuit", integrating 128 deoxyribozyme-based logic gates, 32 input DNA molecules, and 8 two-channel fluorescent outputs across 8 wells.}, address = {National Chemical Bonding Center: Center for Molecular Cybernetics, Division of Experimental Therapeutics, Department of Medicine, Columbia University, New York, New York 10032, USA. jm2236@columbia.edu}, author = {Macdonald, J. and Li, Y. and Sutovic, M. and Lederman, H. and Pendri, K. and Lu, W. and Andrews, B. L. and Stefanovic, D. and Stojanovic, M. N.}, citeulike-article-id = {2940586}, citeulike-linkout-0 = {http://dx.doi.org/10.1021/nl0620684}, citeulike-linkout-1 = {http://pubs.acs.org/doi/abs/10.1021/nl0620684}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/17090098}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=17090098}, doi = {10.1021/nl0620684}, issn = {1530-6984}, journal = {Nano letters}, keywords = {deoxyribozyme, gates, invitro, syntheticbiology}, month = {November}, number = {11}, pages = {2598--2603}, posted-at = {2008-06-29 01:35:01}, priority = {0}, title = {Medium scale integration of molecular logic gates in an automaton.}, url = {http://dx.doi.org/10.1021/nl0620684}, volume = {6}, year = {2006} }

TY - JOUR ID - citeulike:2940586 L3 - citeulike-article-id:2940586 N2 - The assembly of molecular automata that perform increasingly complex tasks, such as game playing, presents an unbiased test of molecular computation. We now report a second-generation deoxyribozyme-based automaton, MAYA-II, which plays a complete game of tic-tac-toe according to a perfect strategy. In silicon terminology, MAYA-II represents the first "medium-scale integrated molecular circuit", integrating 128 deoxyribozyme-based logic gates, 32 input DNA molecules, and 8 two-channel fluorescent outputs across 8 wells. IS - 11 JF - Nano letters SN - 1530-6984 AD - National Chemical Bonding Center: Center for Molecular Cybernetics, Division of Experimental Therapeutics, Department of Medicine, Columbia University, New York, New York 10032, USA. jm2236@columbia.edu EP - 2603 TI - Medium scale integration of molecular logic gates in an automaton. VL - 6 SP - 2598 KW - deoxyribozyme KW - gates KW - invitro KW - syntheticbiology AU - Macdonald, J AU - Li, Y AU - Sutovic, M AU - Lederman, H AU - Pendri, K AU - Lu, W AU - Andrews, BL AU - Stefanovic, D AU - Stojanovic, MN PY - 2006/11// UR - http://dx.doi.org/10.1021/nl0620684 ER -