Anxiety vulnerability is associated with altered anterior cingulate response to an affective appraisal task. Export

@article{citeulike:3338950, abstract = {The anterior cingulate cortex (ACC) is critically involved not only in affective and anxiety processing, but also in error and conflict monitoring. To investigate how anxiety interacts with processing affective ambiguity, 15 anxious and 15 nonanxious individuals were scanned while performing a validated affective appraisal task, in which the fraction of faces of a particular affect or gender was parametrically controlled to provide various levels of ambiguity. The anxious group showed less ventral and greater dorsal ACC activation during ambiguous affective relative to ambiguous gender stimuli. For anxious individuals, dorsal ACC activation was related to a more biased response. Collectively, these data indicate that anxious individuals activate the dorsal and ventral components of the ACC differently during affective appraisal.}, address = {Laboratory of Biological Dynamics and Theoretical Medicine, The Anxiety and Traumatic Stress Disorders Program, Department of Psychiatry, University of California San Diego, La Jolla, California 92037-0985, USA. ansimmons@ucsd.edu}, author = {Simmons, A. and Matthews, S. C. and Feinstein, J. S. and Hitchcock, C. and Paulus, M. P. and Stein, M. B.}, citeulike-article-id = {3338950}, citeulike-linkout-0 = {http://dx.doi.org/10.1097/WNR.0b013e328305b722}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/18580574}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=18580574}, day = {2}, doi = {10.1097/WNR.0b013e328305b722}, issn = {0959-4965}, journal = {Neuroreport}, keywords = {acc, affective, anxiety, appraisal, task}, month = {July}, number = {10}, pages = {1033--1037}, posted-at = {2008-09-26 06:58:03}, priority = {4}, title = {Anxiety vulnerability is associated with altered anterior cingulate response to an affective appraisal task.}, url = {http://dx.doi.org/10.1097/WNR.0b013e328305b722}, volume = {19}, year = {2008} }

TY - JOUR ID - citeulike:3338950 L3 - citeulike-article-id:3338950 N2 - The anterior cingulate cortex (ACC) is critically involved not only in affective and anxiety processing, but also in error and conflict monitoring. To investigate how anxiety interacts with processing affective ambiguity, 15 anxious and 15 nonanxious individuals were scanned while performing a validated affective appraisal task, in which the fraction of faces of a particular affect or gender was parametrically controlled to provide various levels of ambiguity. The anxious group showed less ventral and greater dorsal ACC activation during ambiguous affective relative to ambiguous gender stimuli. For anxious individuals, dorsal ACC activation was related to a more biased response. Collectively, these data indicate that anxious individuals activate the dorsal and ventral components of the ACC differently during affective appraisal. IS - 10 JF - Neuroreport SN - 0959-4965 AD - Laboratory of Biological Dynamics and Theoretical Medicine, The Anxiety and Traumatic Stress Disorders Program, Department of Psychiatry, University of California San Diego, La Jolla, California 92037-0985, USA. ansimmons@ucsd.edu EP - 1037 TI - Anxiety vulnerability is associated with altered anterior cingulate response to an affective appraisal task. VL - 19 SP - 1033 KW - acc KW - affective KW - anxiety KW - appraisal KW - task AU - Simmons, A AU - Matthews, SC AU - Feinstein, JS AU - Hitchcock, C AU - Paulus, MP AU - Stein, MB PY - 2008/07/02/ UR - http://dx.doi.org/10.1097/WNR.0b013e328305b722 ER -