Frameshift detection in prokaryotic genomic sequences. Export

@article{citeulike:5337046, abstract = {We have developed a new method for frameshift detection, a combination of ab initio and alignment-based algorithms, that can serve as a useful tool for sequencing quality control in the next generation sequencing. We evaluated the method's accuracy on test sets of annotated genomic sequences with artificial frameshifts in protein coding regions. These tests have shown that the new method performs comparably to the earlier developed FrameD. On the sets of sequences produced by 454 pyrosequencing with sequence errors recovered by Sanger re-sequencing the accuracy of the method was shown to hold at the same level.}, author = {Kislyuk, Andrey and Lomsadze, Alexandre and Lapidus, Alla L. and Borodovsky, Mark}, citeulike-article-id = {5337046}, citeulike-linkout-0 = {http://view.ncbi.nlm.nih.gov/pubmed/19640832}, citeulike-linkout-1 = {http://www.hubmed.org/display.cgi?uids=19640832}, issn = {1744-5485}, journal = {International journal of bioinformatics research and applications}, keywords = {frameshift, my, prok-seq-cg-pipeline}, number = {4}, pages = {458--477}, posted-at = {2009-08-09 13:48:23}, priority = {2}, title = {Frameshift detection in prokaryotic genomic sequences.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/19640832}, volume = {5}, year = {2009} }

TY - JOUR ID - citeulike:5337046 L3 - citeulike-article-id:5337046 N2 - We have developed a new method for frameshift detection, a combination of ab initio and alignment-based algorithms, that can serve as a useful tool for sequencing quality control in the next generation sequencing. We evaluated the method's accuracy on test sets of annotated genomic sequences with artificial frameshifts in protein coding regions. These tests have shown that the new method performs comparably to the earlier developed FrameD. On the sets of sequences produced by 454 pyrosequencing with sequence errors recovered by Sanger re-sequencing the accuracy of the method was shown to hold at the same level. IS - 4 JF - International journal of bioinformatics research and applications SN - 1744-5485 EP - 477 TI - Frameshift detection in prokaryotic genomic sequences. VL - 5 SP - 458 KW - frameshift KW - my KW - prok-seq-cg-pipeline AU - Kislyuk, Andrey AU - Lomsadze, Alexandre AU - Lapidus, Alla AU - Borodovsky, Mark PY - 2009/// UR - http://view.ncbi.nlm.nih.gov/pubmed/19640832 ER -