Sharing and reusing gene expression profiling data in neuroscience. Export

@article{citeulike:2709681, abstract = {As public availability of gene expression profiling data increases, it is natural to ask how these data can be used by neuroscientists. Here we review the public availability of high-throughput expression data in neuroscience and how it has been reused, and tools that have been developed to facilitate reuse. There is increasing interest in making expression data reuse a routine part of the neuroscience tool-kit, but there are a number of challenges. Data must become more readily available in public databases; efforts to encourage investigators to make data available are important, as is education on the benefits of public data release. Once released, data must be better-annotated. Techniques and tools for data reuse are also in need of improvement. Integration of expression profiling data with neuroscience-specific resources such as anatomical atlases will further increase the value of expression data.}, address = {Department of Psychiatry, UBC Bioinformatics Centre, University of British Columbia, 177 Michael Smith Laboratories 2185 East Mall, Vancouver, BC V6T1Z4, Canada.}, author = {Wan, X. and Pavlidis, P.}, citeulike-article-id = {2709681}, citeulike-linkout-0 = {http://view.ncbi.nlm.nih.gov/pubmed/17917127}, citeulike-linkout-1 = {http://www.hubmed.org/display.cgi?uids=17917127}, issn = {1539-2791}, journal = {Neuroinformatics}, keywords = {cell-models, gene-expression, gene-gene, general-interfaces, informatics, modeling-and-simulation, neuro-computation}, number = {3}, pages = {161--175}, posted-at = {2008-07-17 15:13:38}, priority = {2}, title = {Sharing and reusing gene expression profiling data in neuroscience.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/17917127}, volume = {5}, year = {2007} }

TY - JOUR ID - citeulike:2709681 L3 - citeulike-article-id:2709681 N2 - As public availability of gene expression profiling data increases, it is natural to ask how these data can be used by neuroscientists. Here we review the public availability of high-throughput expression data in neuroscience and how it has been reused, and tools that have been developed to facilitate reuse. There is increasing interest in making expression data reuse a routine part of the neuroscience tool-kit, but there are a number of challenges. Data must become more readily available in public databases; efforts to encourage investigators to make data available are important, as is education on the benefits of public data release. Once released, data must be better-annotated. Techniques and tools for data reuse are also in need of improvement. Integration of expression profiling data with neuroscience-specific resources such as anatomical atlases will further increase the value of expression data. IS - 3 JF - Neuroinformatics SN - 1539-2791 AD - Department of Psychiatry, UBC Bioinformatics Centre, University of British Columbia, 177 Michael Smith Laboratories 2185 East Mall, Vancouver, BC V6T1Z4, Canada. EP - 175 TI - Sharing and reusing gene expression profiling data in neuroscience. VL - 5 SP - 161 KW - cell-models KW - gene-expression KW - gene-gene KW - general-interfaces KW - informatics KW - modeling-and-simulation KW - neuro-computation AU - Wan, X AU - Pavlidis, P PY - 2007/// UR - http://view.ncbi.nlm.nih.gov/pubmed/17917127 ER -