Collective protein dynamics in relation to function

@article{citeulike:2731252, abstract = {Several techniques for the analysis of the internal motions of proteins are available -- separating large collective motions from small, presumably uninteresting motions. Such descriptions are helpful in the characterization of internal motions and provide insight into the energy landscape of proteins. The real challenge, however, is to relate large collective motions to functional properties, such as binding and regulation, or to folding. These issues have been recently addressed in several papers.}, author = {Berendsen, Herman J. C. and Hayward, Steven }, citeulike-article-id = {2731252}, comment = {nice review}, doi = {10.1016/S0959-440X(00)00061-0}, journal = {Current Opinion in Structural Biology}, keywords = {md\_simulation, nma, pca, protein\_dynamics, protein\_structure, review}, month = {April}, number = {2}, pages = {165--169}, posted-at = {2008-04-29 00:03:09}, priority = {2}, title = {Collective protein dynamics in relation to function}, url = {http://dx.doi.org/10.1016/S0959-440X(00)00061-0}, volume = {10}, year = {2000} }

TY - JOUR ID - citeulike:2731252 L3 - citeulike-article-id:2731252 TI - Collective protein dynamics in relation to function JF - Current Opinion in Structural Biology VL - 10 IS - 2 SP - 165 EP - 169 N2 - Several techniques for the analysis of the internal motions of proteins are available -- separating large collective motions from small, presumably uninteresting motions. Such descriptions are helpful in the characterization of internal motions and provide insight into the energy landscape of proteins. The real challenge, however, is to relate large collective motions to functional properties, such as binding and regulation, or to folding. These issues have been recently addressed in several papers. KW - md_simulation KW - nma KW - pca KW - protein_dynamics KW - protein_structure KW - review N1 - nice review AU - Berendsen, Herman AU - Hayward, Steven PY - 2000/04/01/ UR - http://dx.doi.org/10.1016/S0959-440X(00)00061-0 ER -