Precise Subcellular Input Retinotopy and Its Computational Consequences in an Identified Visual Interneuron Export

@article{Peron_2009_precise, abstract = {The Lobula Giant Movement Detector (LGMD) is a higher-order visual interneuron of Orthopteran insects that responds preferentially to objects approaching on a collision course. It receives excitatory input from an entire visual hemifield that anatomical evidence suggests is retinotopic. We show that this excitatory projection activates calcium-permeable nicotinic acetylcholine receptors. In vivo calcium imaging reveals that the excitatory projection preserves retinotopy down to the level of a single ommatidium. Examining the impact of retinotopy on the LGMD's computational properties, we show that sublinear synaptic summation can explain orientation preference in this cell. Exploring retinotopy's impact on directional selectivity leads us to infer that the excitatory input to the LGMD is intrinsically directionally selective. Our results show that precise retinotopy has implications for the dendritic integration of visual information in a single neuron.}, author = {Peron, Simon P. and Jones, Peter W. and Gabbiani, Fabrizio}, citeulike-article-id = {5870683}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.neuron.2009.09.010}, citeulike-linkout-1 = {http://linkinghub.elsevier.com/retrieve/pii/S0896627309006928}, day = {24}, doi = {10.1016/j.neuron.2009.09.010}, issn = {08966273}, journal = {Neuron}, keywords = {coding, locust, motion, visual}, month = {September}, number = {6}, pages = {830--842}, posted-at = {2009-10-27 08:35:18}, priority = {2}, title = {Precise Subcellular Input Retinotopy and Its Computational Consequences in an Identified Visual Interneuron}, url = {http://dx.doi.org/10.1016/j.neuron.2009.09.010}, volume = {63}, year = {2009} }

TY - JOUR ID - Peron_2009_precise L3 - citeulike-article-id:5870683 N2 - The Lobula Giant Movement Detector (LGMD) is a higher-order visual interneuron of Orthopteran insects that responds preferentially to objects approaching on a collision course. It receives excitatory input from an entire visual hemifield that anatomical evidence suggests is retinotopic. We show that this excitatory projection activates calcium-permeable nicotinic acetylcholine receptors. In vivo calcium imaging reveals that the excitatory projection preserves retinotopy down to the level of a single ommatidium. Examining the impact of retinotopy on the LGMD's computational properties, we show that sublinear synaptic summation can explain orientation preference in this cell. Exploring retinotopy's impact on directional selectivity leads us to infer that the excitatory input to the LGMD is intrinsically directionally selective. Our results show that precise retinotopy has implications for the dendritic integration of visual information in a single neuron. IS - 6 JF - Neuron SN - 08966273 EP - 842 TI - Precise Subcellular Input Retinotopy and Its Computational Consequences in an Identified Visual Interneuron VL - 63 SP - 830 KW - coding KW - locust KW - motion KW - visual AU - Peron, Simon AU - Jones, Peter AU - Gabbiani, Fabrizio PY - 2009/September/24/ UR - http://dx.doi.org/10.1016/j.neuron.2009.09.010 ER -