Comparative Pathway Analyzer--a web server for comparative analysis, clustering and visualization of metabolic networks in multiple organisms. Export

@article{citeulike:2881781, abstract = {In order to understand the phenotype of any living system, it is essential to not only investigate its genes, but also the specific metabolic pathway variant of the organism of interest, ideally in comparison with other organisms. The Comparative Pathway Analyzer, CPA, calculates and displays the differences in metabolic reaction content between two sets of organisms. Because results are highly dependent on the distribution of organisms into these two sets and the appropriate definition of these sets often is not easy, we provide hierarchical clustering methods for the identification of significant groupings. CPA also visualizes the reaction content of several organisms simultaneously allowing easy comparison. Reaction annotation data and maps for visualizing the results are taken from the KEGG database. Additionally, users can upload their own annotation data. This website is free and open to all users and there is no login requirement. It is available at https://www.cebitec.uni-bielefeld.de/groups/brf/software/cpa/index.html.}, address = {Center for Biotechnology (CeBiTec), Bielefeld University, D-33594 Bielefeld, Germany, Bioinformatics Research Centre, University of Glasgow, Glasgow G12 8QQ, UK, Institut f\"{u}r Genomforschung und Systembiologie, AG Genominformatik, Faculty of Technology and Bioinformatics Resource Facility (BRF), Bielefeld University, D-33594 Bielefeld, Germany.}, author = {Oehm, Sebastian and Gilbert, David and Tauch, Andreas and Stoye, Jens and Goesmann, Alexander}, citeulike-article-id = {2881781}, citeulike-linkout-0 = {http://dx.doi.org/10.1093/nar/gkn284}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/18539612}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=18539612}, day = {1}, doi = {10.1093/nar/gkn284}, issn = {1362-4962}, journal = {Nucleic acids research}, keywords = {cpa}, month = {July}, number = {Web Server issue}, posted-at = {2008-08-19 09:05:35}, priority = {2}, title = {Comparative Pathway Analyzer--a web server for comparative analysis, clustering and visualization of metabolic networks in multiple organisms.}, url = {http://dx.doi.org/10.1093/nar/gkn284}, volume = {36}, year = {2008} }

TY - JOUR ID - citeulike:2881781 L3 - citeulike-article-id:2881781 N2 - In order to understand the phenotype of any living system, it is essential to not only investigate its genes, but also the specific metabolic pathway variant of the organism of interest, ideally in comparison with other organisms. The Comparative Pathway Analyzer, CPA, calculates and displays the differences in metabolic reaction content between two sets of organisms. Because results are highly dependent on the distribution of organisms into these two sets and the appropriate definition of these sets often is not easy, we provide hierarchical clustering methods for the identification of significant groupings. CPA also visualizes the reaction content of several organisms simultaneously allowing easy comparison. Reaction annotation data and maps for visualizing the results are taken from the KEGG database. Additionally, users can upload their own annotation data. This website is free and open to all users and there is no login requirement. It is available at https://www.cebitec.uni-bielefeld.de/groups/brf/software/cpa/index.html. IS - Web Server issue JF - Nucleic acids research SN - 1362-4962 AD - Center for Biotechnology (CeBiTec), Bielefeld University, D-33594 Bielefeld, Germany, Bioinformatics Research Centre, University of Glasgow, Glasgow G12 8QQ, UK, Institut für Genomforschung und Systembiologie, AG Genominformatik, Faculty of Technology and Bioinformatics Resource Facility (BRF), Bielefeld University, D-33594 Bielefeld, Germany. TI - Comparative Pathway Analyzer--a web server for comparative analysis, clustering and visualization of metabolic networks in multiple organisms. VL - 36 KW - cpa AU - Oehm, Sebastian AU - Gilbert, David AU - Tauch, Andreas AU - Stoye, Jens AU - Goesmann, Alexander PY - 2008/07/01/ UR - http://dx.doi.org/10.1093/nar/gkn284 ER -