Systems biology: from physiology to gene regulation Export

@article{7764, abstract = {The discovery of DNA and its essential role in cellular function has revolutionized the science of biology. Rapid progress in biology has led to new and exciting discoveries that promise to uncover the basic underpinnings of life. As biology becomes quantitative, the role of mathematics becomes important. Furthermore, the complex nature of biology systems makes an integrative systems approach essential. In this article, the author focused on two areas where control theory can play a key role. Mathematical modeling has not only helped reverse engineer biological systems, but it has also made forward engineering possible. If this opportunity is seized, control theory becomes the bridge between the technological sciences and the life sciences.}, author = {Khammash, M. and El-Samad, H.}, citeulike-article-id = {3561539}, citeulike-linkout-0 = {http://dx.doi.org/10.1109/MCS.2004.1316654}, doi = {10.1109/MCS.2004.1316654}, issn = {0272-1708}, journal = {Control Systems Magazine, IEEE}, keywords = {approach, biocontrol, biology, biophysics, calcium, cellular, control, endocrinology, engineering, feedback, function, gene, homeostasis, integral, integrative, mathematical, model, modeling, molecular, physiological, physiology, regulation, systems, theory}, number = {4}, pages = {62--76}, posted-at = {2008-11-17 19:41:13}, priority = {3}, title = {Systems biology: from physiology to gene regulation}, url = {http://dx.doi.org/10.1109/MCS.2004.1316654}, volume = {24}, year = {2004} }

TY - JOUR ID - 7764 L3 - citeulike-article-id:3561539 N2 - The discovery of DNA and its essential role in cellular function has revolutionized the science of biology. Rapid progress in biology has led to new and exciting discoveries that promise to uncover the basic underpinnings of life. As biology becomes quantitative, the role of mathematics becomes important. Furthermore, the complex nature of biology systems makes an integrative systems approach essential. In this article, the author focused on two areas where control theory can play a key role. Mathematical modeling has not only helped reverse engineer biological systems, but it has also made forward engineering possible. If this opportunity is seized, control theory becomes the bridge between the technological sciences and the life sciences. IS - 4 JF - Control Systems Magazine, IEEE SN - 0272-1708 EP - 76 TI - Systems biology: from physiology to gene regulation VL - 24 SP - 62 KW - approach KW - biocontrol KW - biology KW - biophysics KW - calcium KW - cellular KW - control KW - endocrinology KW - engineering KW - feedback KW - function KW - gene KW - homeostasis KW - integral KW - integrative KW - mathematical KW - model KW - modeling KW - molecular KW - physiological KW - physiology KW - regulation KW - systems KW - theory AU - Khammash, M AU - El-Samad, H PY - 2004/// UR - http://dx.doi.org/10.1109/MCS.2004.1316654 ER -