Propofol by infusion protocol for ED procedural sedation. Export

@article{citeulike:822260, abstract = {INTRODUCTION: Propofol is an effective agent for use in procedural sedation and analgesia (PSA). Most ED studies have used a bolus-dosed protocol. We evaluated the efficacy, complication rate, and satisfaction among caregivers and patients while using an infusion-dosed protocol of propofol for PSA in our ED. METHODS: A prospective, observational study was performed in our academic ED. Propofol use was at the discretion of the ordering physician and dosed by predetermined infusion protocol. Variables measured included adverse events, times of sedation, procedure, and recovery. Patient and provider satisfaction were measured using a 10-cm visual analog scale. RESULTS: Fifty patients were enrolled over 18 months. Procedures were varied, and all were successfully completed. The mean propofol dose was 174 mg (SD = 164 mg). Average times to sedation (4.6 minutes, SD = 2.6 minutes) and recovery (8.2 minutes, SD = 5.8 minutes) were short. Complications included 8 patients with respiratory depression and 6 with hypotension, all easily reversible. Satisfaction scores were uniformly high. Only 34\% of patients had any memory of the procedure, and 94\% would agree to use it again if necessary. CONCLUSIONS: Infusion-dosed propofol is effective for ED PSA. Total doses, effectiveness, satisfaction rates, and complications of infusion-dosed propofol are comparable to findings from studies using bolus-dosed protocols.}, address = {Division of Emergency Medicine, University of Washington School of Medicine, Seattle, WA, USA.}, author = {Frank, L. R. and Strote, J. and Hauff, S. R. and Bigelow, S. K. and Fay, K.}, citeulike-article-id = {822260}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.ajem.2006.02.008}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/16938600}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=16938600}, comment = {Describes positive experience with a propofol drip for procedural sedation in the ED.}, doi = {10.1016/j.ajem.2006.02.008}, issn = {0735-6757}, journal = {Am J Emerg Med}, keywords = {drugs, emergency, sedation}, month = {September}, number = {5}, pages = {599--602}, posted-at = {2006-08-30 17:53:59}, priority = {0}, title = {Propofol by infusion protocol for ED procedural sedation.}, url = {http://dx.doi.org/10.1016/j.ajem.2006.02.008}, volume = {24}, year = {2006} }

TY - JOUR ID - citeulike:822260 L3 - citeulike-article-id:822260 N2 - INTRODUCTION: Propofol is an effective agent for use in procedural sedation and analgesia (PSA). Most ED studies have used a bolus-dosed protocol. We evaluated the efficacy, complication rate, and satisfaction among caregivers and patients while using an infusion-dosed protocol of propofol for PSA in our ED. METHODS: A prospective, observational study was performed in our academic ED. Propofol use was at the discretion of the ordering physician and dosed by predetermined infusion protocol. Variables measured included adverse events, times of sedation, procedure, and recovery. Patient and provider satisfaction were measured using a 10-cm visual analog scale. RESULTS: Fifty patients were enrolled over 18 months. Procedures were varied, and all were successfully completed. The mean propofol dose was 174 mg (SD = 164 mg). Average times to sedation (4.6 minutes, SD = 2.6 minutes) and recovery (8.2 minutes, SD = 5.8 minutes) were short. Complications included 8 patients with respiratory depression and 6 with hypotension, all easily reversible. Satisfaction scores were uniformly high. Only 34% of patients had any memory of the procedure, and 94% would agree to use it again if necessary. CONCLUSIONS: Infusion-dosed propofol is effective for ED PSA. Total doses, effectiveness, satisfaction rates, and complications of infusion-dosed propofol are comparable to findings from studies using bolus-dosed protocols. IS - 5 JF - Am J Emerg Med SN - 0735-6757 AD - Division of Emergency Medicine, University of Washington School of Medicine, Seattle, WA, USA. EP - 602 TI - Propofol by infusion protocol for ED procedural sedation. VL - 24 SP - 599 KW - drugs KW - emergency KW - sedation N1 - Describes positive experience with a propofol drip for procedural sedation in the ED. AU - Frank, LR AU - Strote, J AU - Hauff, SR AU - Bigelow, SK AU - Fay, K PY - 2006/09// UR - http://dx.doi.org/10.1016/j.ajem.2006.02.008 ER -