Initial Severity and Antidepressant Benefits: A Meta-Analysis of Data Submitted to the Food and Drug Administration Export

@article{citeulike:2427639, abstract = {Kirsch and colleagues show that, in antidepressant trials, there is a greater difference in efficacy between drug and placebo amongst more severely depressed patients. However, this difference seems to result from a poorer response to placebo amongst more depressed patients.}, author = {Kirsch, Irving and Deacon, Brett J. and Huedo-Medina, Tania B. and Scoboria, Alan and Moore, Thomas J. and Johnson, Blair T.}, citeulike-article-id = {2427639}, citeulike-linkout-0 = {http://dx.doi.org/10.1371/journal.pmed.0050045}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/18303940}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=18303940}, day = {26}, doi = {10.1371/journal.pmed.0050045}, issn = {1549-1676}, journal = {PLoS Med}, keywords = {antidepressiva, depressie, medicatie}, month = {February}, number = {2}, pages = {e45+}, posted-at = {2009-06-21 12:00:02}, priority = {2}, publisher = {Public Library of Science}, title = {Initial Severity and Antidepressant Benefits: A Meta-Analysis of Data Submitted to the Food and Drug Administration}, url = {http://dx.doi.org/10.1371/journal.pmed.0050045}, volume = {5}, year = {2008} }

TY - JOUR ID - citeulike:2427639 L3 - citeulike-article-id:2427639 N2 - Kirsch and colleagues show that, in antidepressant trials, there is a greater difference in efficacy between drug and placebo amongst more severely depressed patients. However, this difference seems to result from a poorer response to placebo amongst more depressed patients. IS - 2 JF - PLoS Med SN - 1549-1676 TI - Initial Severity and Antidepressant Benefits: A Meta-Analysis of Data Submitted to the Food and Drug Administration PB - Public Library of Science VL - 5 SP - e45 KW - antidepressiva KW - depressie KW - medicatie AU - Kirsch, Irving AU - Deacon, Brett AU - Huedo-Medina, Tania AU - Scoboria, Alan AU - Moore, Thomas AU - Johnson, Blair PY - 2008/02/26/ UR - http://dx.doi.org/10.1371/journal.pmed.0050045 ER -