Study design in fMRI: Basic principles.

by: Edson Amaro, Gareth J J Barker

Brain Cogn (18 January 2006)

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Abstract

There is a wide range of functional magnetic resonance imaging (fMRI) study designs available for the neuroscientist who wants to investigate cognition. In this manuscript we review some aspects of fMRI study design, including cognitive comparison strategies (factorial, parametric designs), and stimulus presentation possibilities (block, event-related, rapid event-related, mixed, and self-driven experiment designs) along with technical aspects, such as limitations of signal to noise ratio, spatial, and temporal resolution. We also discuss methods to deal with cases where scanning parameters become the limiting factor (parallel acquisitions, variable jittered designs, scanner acoustic noise strategies).

@article{citeulike:515764, abstract = {There is a wide range of functional magnetic resonance imaging (fMRI) study designs available for the neuroscientist who wants to investigate cognition. In this manuscript we review some aspects of fMRI study design, including cognitive comparison strategies (factorial, parametric designs), and stimulus presentation possibilities (block, event-related, rapid event-related, mixed, and self-driven experiment designs) along with technical aspects, such as limitations of signal to noise ratio, spatial, and temporal resolution. We also discuss methods to deal with cases where scanning parameters become the limiting factor (parallel acquisitions, variable jittered designs, scanner acoustic noise strategies).}, address = {Neuroimaging Research Group, Institute of Psychiatry, King’s College, University College, London, UK; Institute of Radiology, LIM 44—Faculdade de Medicina, Universidade de S\~{a}o Paulo, Brazil.}, author = {Amaro, Edson and Barker, Gareth J J. }, citeulike-article-id = {515764}, doi = {http://dx.doi.org/10.1016/j.bandc.2005.11.009}, issn = {0278-2626}, journal = {Brain Cogn}, keywords = {fmri, research\_design, study\_design}, month = {January}, posted-at = {2008-05-06 20:04:05}, priority = {2}, title = {Study design in fMRI: Basic principles.}, url = {http://dx.doi.org/10.1016/j.bandc.2005.11.009}, year = {2006} }

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TY - JOUR ID - citeulike:515764 L3 - citeulike-article-id:515764 TI - Study design in fMRI: Basic principles. JF - Brain Cogn AD - Neuroimaging Research Group, Institute of Psychiatry, King’s College, University College, London, UK; Institute of Radiology, LIM 44—Faculdade de Medicina, Universidade de São Paulo, Brazil. SN - 0278-2626 N2 - There is a wide range of functional magnetic resonance imaging (fMRI) study designs available for the neuroscientist who wants to investigate cognition. In this manuscript we review some aspects of fMRI study design, including cognitive comparison strategies (factorial, parametric designs), and stimulus presentation possibilities (block, event-related, rapid event-related, mixed, and self-driven experiment designs) along with technical aspects, such as limitations of signal to noise ratio, spatial, and temporal resolution. We also discuss methods to deal with cases where scanning parameters become the limiting factor (parallel acquisitions, variable jittered designs, scanner acoustic noise strategies). KW - fmri KW - research_design KW - study_design AU - Amaro, Edson AU - Barker, Gareth J PY - 2006/01/18/ UR - http://dx.doi.org/10.1016/j.bandc.2005.11.009 ER -

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