Specification of Arabidopsis floral meristem identity by repression of flowering time genes Export

@article{citeulike:3110296, abstract = {Flowering plants produce floral meristems in response to intrinsic and extrinsic flowering inductive signals. In Arabidopsis, the floral meristem identity genes LEAFY (LFY) and APETALA1 (AP1) are activated to play a pivotal role in specifying floral meristems during floral transition. We show here that the emerging floral meristems require AP1 to partly specify their floral identities by directly repressing a group of flowering time genes, including SHORT VEGETATIVE PHASE (SVP), AGAMOUS-LIKE 24 (AGL24) and SUPPRESSOR OF OVEREXPRESSION OF CO1 (SOC1). In wild-type plants, these flowering time genes are normally downregulated in emerging floral meristems. In the absence of AP1, these genes are ectopically expressed, transforming floral meristems into shoot meristems. By post-translational activation of an AP1-GR fusion protein and chromatin immunoprecipitation assays, we further demonstrate the repression of these flowering time genes by induced AP1 activity and in vivo AP1 binding to the cis-regulatory regions of these genes. These findings indicate that once AP1 is activated during the floral transition, it acts partly as a master repressor in floral meristems by directly suppressing the expression of flowering time genes, thus preventing the continuation of the shoot developmental program. 10.1242/dev.003103}, author = {Liu, Chang and Zhou, Jing and Bracha-Drori, Keren and Yalovsky, Shaul and Ito, Toshiro and Yu, Hao}, citeulike-article-id = {3110296}, citeulike-linkout-0 = {http://dx.doi.org/10.1242/dev.003103}, citeulike-linkout-1 = {http://dev.biologists.org/cgi/content/abstract/134/10/1901}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/17428825}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=17428825}, day = {15}, doi = {10.1242/dev.003103}, journal = {Development}, keywords = {agl24, ap1, soc1}, month = {May}, number = {10}, pages = {1901--1910}, posted-at = {2008-08-11 23:43:10}, priority = {2}, title = {Specification of Arabidopsis floral meristem identity by repression of flowering time genes}, url = {http://dx.doi.org/10.1242/dev.003103}, volume = {134}, year = {2007} }

TY - JOUR ID - citeulike:3110296 L3 - citeulike-article-id:3110296 N2 - Flowering plants produce floral meristems in response to intrinsic and extrinsic flowering inductive signals. In Arabidopsis, the floral meristem identity genes LEAFY (LFY) and APETALA1 (AP1) are activated to play a pivotal role in specifying floral meristems during floral transition. We show here that the emerging floral meristems require AP1 to partly specify their floral identities by directly repressing a group of flowering time genes, including SHORT VEGETATIVE PHASE (SVP), AGAMOUS-LIKE 24 (AGL24) and SUPPRESSOR OF OVEREXPRESSION OF CO1 (SOC1). In wild-type plants, these flowering time genes are normally downregulated in emerging floral meristems. In the absence of AP1, these genes are ectopically expressed, transforming floral meristems into shoot meristems. By post-translational activation of an AP1-GR fusion protein and chromatin immunoprecipitation assays, we further demonstrate the repression of these flowering time genes by induced AP1 activity and in vivo AP1 binding to the cis-regulatory regions of these genes. These findings indicate that once AP1 is activated during the floral transition, it acts partly as a master repressor in floral meristems by directly suppressing the expression of flowering time genes, thus preventing the continuation of the shoot developmental program. 10.1242/dev.003103 IS - 10 JF - Development EP - 1910 TI - Specification of Arabidopsis floral meristem identity by repression of flowering time genes VL - 134 SP - 1901 KW - agl24 KW - ap1 KW - soc1 AU - Liu, Chang AU - Zhou, Jing AU - Bracha-Drori, Keren AU - Yalovsky, Shaul AU - Ito, Toshiro AU - Yu, Hao PY - 2007/05/15/ UR - http://dx.doi.org/10.1242/dev.003103 ER -