The association of fruits, vegetables, antioxidant vitamins and fibre intake with high-sensitivity C-reactive protein: sex and body mass index interactions. Export

@article{citeulike:5277258, abstract = {OBJECTIVE: To study the associations of fruits, vegetables, antioxidant vitamins and fibre intake with high-sensitivity C-reactive protein (hs-CRP). Existing literature on these associations is scarce and has rendered conflicting results. METHODS: Cross-sectional study of 1060 individuals (675 women, 385 men), representative of the non-institutionalized population, aged >or=18 years, in Porto, Portugal (70\% participation rate). Diet over the previous year was assessed with a validated food frequency questionnaire. Associations between diet and hs-CRP (categorized into <1, 1-3, >3 to <or=10 mg/l) were obtained from ordinal logistic regression models (odds ratio, 95\% confidence intervals-OR, 95\% CI) adjusted for sociodemographic and behavioural variables. RESULTS: In normal weight men (body mass index (BMI) <25.0 kg/m(2)), for each 100 g increase in fruit and vegetable intake, there was 30\% less probability of changing of hs-CRP category (no risk to moderate risk, or moderate to high risk). Protective associations were also observed between hs-CRP and fruits (OR=0.73, 95\% CI 0.56-0.96 per 100 g/day), vegetables (OR=0.55, 95\% CI 0.35-0.86 per 100 g/day), vitamin C (OR=0.34, 95\% CI 0.14-0.80 per 10 mg/day) and vitamin E (OR=0.14, 95\% CI 0.02-0.88 per 1000 retinol equivalents per day). Overall, associations tended to be weaker in overweight participants. In men (BMI >or=25.0 kg/m(2)), fibre was also negatively associated with hs-CRP. In women, no significant associations were found between dietary variables and hs-CRP. A significant modification effect of the evaluated associations was found by sex for fruits and vegetables, vitamin C and fibre, but not by BMI. CONCLUSION: Intake of fruits and vegetables, vitamin C, E and fibre were negatively associated with hs-CRP in men.}, author = {Oliveira, A. and Rodr\'{\i}guez-Artalejo, F. and Lopes, C.}, citeulike-article-id = {5277258}, citeulike-linkout-0 = {http://dx.doi.org/10.1038/ejcn.2009.61}, citeulike-linkout-1 = {http://dx.doi.org/10.1038/ejcn200961a}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/19623199}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=19623199}, day = {22}, doi = {10.1038/ejcn.2009.61}, issn = {1476-5640}, journal = {European journal of clinical nutrition}, keywords = {c-reactive-protein, inflammation}, month = {November}, number = {11}, pages = {1345--1352}, posted-at = {2009-11-04 22:16:59}, priority = {2}, publisher = {Nature Publishing Group}, title = {The association of fruits, vegetables, antioxidant vitamins and fibre intake with high-sensitivity C-reactive protein: sex and body mass index interactions.}, url = {http://dx.doi.org/10.1038/ejcn.2009.61}, volume = {63}, year = {2009} }

TY - JOUR ID - citeulike:5277258 L3 - citeulike-article-id:5277258 N2 - OBJECTIVE: To study the associations of fruits, vegetables, antioxidant vitamins and fibre intake with high-sensitivity C-reactive protein (hs-CRP). Existing literature on these associations is scarce and has rendered conflicting results. METHODS: Cross-sectional study of 1060 individuals (675 women, 385 men), representative of the non-institutionalized population, aged >or=18 years, in Porto, Portugal (70% participation rate). Diet over the previous year was assessed with a validated food frequency questionnaire. Associations between diet and hs-CRP (categorized into <1, 1-3, >3 to <or=10 mg/l) were obtained from ordinal logistic regression models (odds ratio, 95% confidence intervals-OR, 95% CI) adjusted for sociodemographic and behavioural variables. RESULTS: In normal weight men (body mass index (BMI) <25.0 kg/m(2)), for each 100 g increase in fruit and vegetable intake, there was 30% less probability of changing of hs-CRP category (no risk to moderate risk, or moderate to high risk). Protective associations were also observed between hs-CRP and fruits (OR=0.73, 95% CI 0.56-0.96 per 100 g/day), vegetables (OR=0.55, 95% CI 0.35-0.86 per 100 g/day), vitamin C (OR=0.34, 95% CI 0.14-0.80 per 10 mg/day) and vitamin E (OR=0.14, 95% CI 0.02-0.88 per 1000 retinol equivalents per day). Overall, associations tended to be weaker in overweight participants. In men (BMI >or=25.0 kg/m(2)), fibre was also negatively associated with hs-CRP. In women, no significant associations were found between dietary variables and hs-CRP. A significant modification effect of the evaluated associations was found by sex for fruits and vegetables, vitamin C and fibre, but not by BMI. CONCLUSION: Intake of fruits and vegetables, vitamin C, E and fibre were negatively associated with hs-CRP in men. IS - 11 JF - European journal of clinical nutrition SN - 1476-5640 EP - 1352 TI - The association of fruits, vegetables, antioxidant vitamins and fibre intake with high-sensitivity C-reactive protein: sex and body mass index interactions. PB - Nature Publishing Group VL - 63 SP - 1345 KW - c-reactive-protein KW - inflammation AU - Oliveira, A AU - Rodríguez-Artalejo, F AU - Lopes, C PY - 2009/11/22/ UR - http://dx.doi.org/10.1038/ejcn.2009.61 ER -