Function prediction and protein networks. Export

@article{citeulike:331912, abstract = {In the genomics era, the interactions between proteins are at the center of attention. Genomic-context methods used to predict these interactions have been put on a quantitative basis, revealing that they are at least on an equal footing with genomics experimental data. A survey of experimentally confirmed predictions proves the applicability of these methods, and new concepts to predict protein interactions in eukaryotes have been described. Finally, the interaction networks that can be obtained by combining the predicted pair-wise interactions have enough internal structure to detect higher levels of organization, such as 'functional modules'.}, address = {Nijmegen Center for Molecular Life Sciences, Center for Molecular and Biomolecular Informatics, Toernooiveld 1, 6525 ED, Nijmegen, The Netherlands. huynen@cmbi.kun.nl}, author = {Huynen, M. A. and Snel, B. and von Mering, C. and Bork, P.}, citeulike-article-id = {331912}, citeulike-linkout-0 = {http://view.ncbi.nlm.nih.gov/pubmed/12648675}, citeulike-linkout-1 = {http://www.hubmed.org/display.cgi?uids=12648675}, issn = {0955-0674}, journal = {Curr Opin Cell Biol}, keywords = {functional, network, protein}, month = {April}, number = {2}, pages = {191--198}, posted-at = {2007-04-28 13:12:17}, priority = {5}, title = {Function prediction and protein networks.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/12648675}, volume = {15}, year = {2003} }

TY - JOUR ID - citeulike:331912 L3 - citeulike-article-id:331912 N2 - In the genomics era, the interactions between proteins are at the center of attention. Genomic-context methods used to predict these interactions have been put on a quantitative basis, revealing that they are at least on an equal footing with genomics experimental data. A survey of experimentally confirmed predictions proves the applicability of these methods, and new concepts to predict protein interactions in eukaryotes have been described. Finally, the interaction networks that can be obtained by combining the predicted pair-wise interactions have enough internal structure to detect higher levels of organization, such as 'functional modules'. IS - 2 JF - Curr Opin Cell Biol SN - 0955-0674 AD - Nijmegen Center for Molecular Life Sciences, Center for Molecular and Biomolecular Informatics, Toernooiveld 1, 6525 ED, Nijmegen, The Netherlands. huynen@cmbi.kun.nl EP - 198 TI - Function prediction and protein networks. VL - 15 SP - 191 KW - functional KW - network KW - protein AU - Huynen, MA AU - Snel, B AU - von Mering, C AU - Bork, P PY - 2003/04// UR - http://view.ncbi.nlm.nih.gov/pubmed/12648675 ER -