Very low gene duplication rate in the yeast genome. Export

@article{citeulike:3292425, abstract = {The gene duplication rate in the yeast genome is estimated without assuming the molecular clock model to be approximately 0.01 to 0.06 per gene per billion years; this rate is two orders of magnitude lower than a previous estimate based on the molecular clock model. This difference is explained by extensive concerted evolution via gene conversion between duplicated genes, which violates the assumption of the molecular clock in the analyses of duplicated genes. The average length of the period of concerted evolution and the gene conversion rate are estimated to be approximately 25 million years and approximately 28 times the mutation rate, respectively.}, address = {Human Genetics Center, School of Public Health, University of Texas Health Science Center, 1200 Hermann Pressler, Houston, TX 77030, USA.}, author = {Gao, L. Z. and Innan, H.}, citeulike-article-id = {3292425}, citeulike-linkout-0 = {http://dx.doi.org/10.1126/science.1102033}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/15550669}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=15550669}, day = {19}, doi = {10.1126/science.1102033}, issn = {1095-9203}, journal = {Science (New York, N.Y.)}, keywords = {dosage, duplicability, duplication}, month = {November}, number = {5700}, pages = {1367--1370}, posted-at = {2008-09-19 11:01:02}, priority = {2}, title = {Very low gene duplication rate in the yeast genome.}, url = {http://dx.doi.org/10.1126/science.1102033}, volume = {306}, year = {2004} }

TY - JOUR ID - citeulike:3292425 L3 - citeulike-article-id:3292425 N2 - The gene duplication rate in the yeast genome is estimated without assuming the molecular clock model to be approximately 0.01 to 0.06 per gene per billion years; this rate is two orders of magnitude lower than a previous estimate based on the molecular clock model. This difference is explained by extensive concerted evolution via gene conversion between duplicated genes, which violates the assumption of the molecular clock in the analyses of duplicated genes. The average length of the period of concerted evolution and the gene conversion rate are estimated to be approximately 25 million years and approximately 28 times the mutation rate, respectively. IS - 5700 JF - Science (New York, N.Y.) SN - 1095-9203 AD - Human Genetics Center, School of Public Health, University of Texas Health Science Center, 1200 Hermann Pressler, Houston, TX 77030, USA. EP - 1370 TI - Very low gene duplication rate in the yeast genome. VL - 306 SP - 1367 KW - dosage KW - duplicability KW - duplication AU - Gao, LZ AU - Innan, H PY - 2004/11/19/ UR - http://dx.doi.org/10.1126/science.1102033 ER -