Gene Transposition as a Cause of Hybrid Sterility in Drosophila Export

@article{citeulike:836986, abstract = {We describe reproductive isolation caused by a gene transposition. In certain Drosophila melanogaster-D. simulans hybrids, hybrid male sterility is caused by the lack of a single-copy gene essential for male fertility, JYAlpha. This gene is located on the fourth chromosome of D. melanogaster but on the third chromosome of D. simulans. Genomic and molecular analyses show that JYAlpha transposed to the third chromosome during the evolutionary history of the D. simulans lineage. Because of this transposition, a fraction of hybrids completely lack JYAlpha and are sterile, representing reproductive isolation without sequence evolution. 10.1126/science.1128721}, author = {Masly, John P. and Jones, Corbin D. and Noor, Mohamed A. and Locke, John and Orr, Allen H.}, citeulike-article-id = {836986}, citeulike-linkout-0 = {http://dx.doi.org/10.1126/science.1128721}, citeulike-linkout-1 = {http://www.sciencemag.org/cgi/content/abstract/313/5792/1448}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/16960009}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=16960009}, day = {8}, doi = {10.1126/science.1128721}, journal = {Science}, keywords = {gene\_loss, speciation}, month = {September}, number = {5792}, pages = {1448--1450}, posted-at = {2008-08-06 16:29:58}, priority = {2}, title = {Gene Transposition as a Cause of Hybrid Sterility in Drosophila}, url = {http://dx.doi.org/10.1126/science.1128721}, volume = {313}, year = {2006} }

TY - JOUR ID - citeulike:836986 L3 - citeulike-article-id:836986 N2 - We describe reproductive isolation caused by a gene transposition. In certain Drosophila melanogaster-D. simulans hybrids, hybrid male sterility is caused by the lack of a single-copy gene essential for male fertility, JYAlpha. This gene is located on the fourth chromosome of D. melanogaster but on the third chromosome of D. simulans. Genomic and molecular analyses show that JYAlpha transposed to the third chromosome during the evolutionary history of the D. simulans lineage. Because of this transposition, a fraction of hybrids completely lack JYAlpha and are sterile, representing reproductive isolation without sequence evolution. 10.1126/science.1128721 IS - 5792 JF - Science EP - 1450 TI - Gene Transposition as a Cause of Hybrid Sterility in Drosophila VL - 313 SP - 1448 KW - gene_loss KW - speciation AU - Masly, John AU - Jones, Corbin AU - Noor, Mohamed AU - Locke, John AU - Orr, Allen PY - 2006/09/08/ UR - http://dx.doi.org/10.1126/science.1128721 ER -