GATE: Software for the Analysis and Visualization of High-Dimensional Time-series Expression Data Export

@article{citeulike:6080235, abstract = {Summary: We present Grid Analysis of Time-series Expression (GATE), an integrated computational software platform for the analysis and visualization of high-dimensional bio-molecular time-series. GATE uses a correlation-based clustering algorithm to arrange molecular time-series on a two-dimensional hexagonal array and dynamically colors individual hexagons according to the expression level of the molecular component to which they are assigned, to create animated movies of systems-level molecular regulatory dynamics. In order to infer potential regulatory control mechanisms from patterns of correlation, GATE also allows interactive interrogation of movies against a wide variety of prior knowledge datasets. GATE movies can be paused and are interactive, allowing users to reconstruct networks and perform functional enrichment analyses. Movies created with GATE can be saved in Flash format and can be inserted directly into PDF manuscript files as interactive figures. Availability: GATE is available for download and is free for academic use from http://amp.pharm.mssm.edu/maayan-lab/gate.htm Contact: avi.maayan@mssm.edu 10.1093/bioinformatics/btp628}, author = {MacArthur, Ben D. and Lachmann, Alexander and Lemischka, Ihor R. and Ma'ayan, Avi}, citeulike-article-id = {6080235}, citeulike-linkout-0 = {http://dx.doi.org/10.1093/bioinformatics/btp628}, citeulike-linkout-1 = {http://bioinformatics.oxfordjournals.org/content/btp628v1/.abstract}, citeulike-linkout-2 = {http://bioinformatics.oxfordjournals.org/content/btp628v1/.full.pdf}, citeulike-linkout-3 = {http://view.ncbi.nlm.nih.gov/pubmed/19892805}, citeulike-linkout-4 = {http://www.hubmed.org/display.cgi?uids=19892805}, day = {5}, doi = {10.1093/bioinformatics/btp628}, journal = {Bioinformatics}, keywords = {bioinformatics, expression, gene, proteomics, time-course}, month = {November}, pages = {btp628+}, posted-at = {2009-11-06 15:53:56}, priority = {2}, title = {GATE: Software for the Analysis and Visualization of High-Dimensional Time-series Expression Data}, url = {http://dx.doi.org/10.1093/bioinformatics/btp628}, year = {2009} }

TY - JOUR ID - citeulike:6080235 L3 - citeulike-article-id:6080235 N2 - Summary: We present Grid Analysis of Time-series Expression (GATE), an integrated computational software platform for the analysis and visualization of high-dimensional bio-molecular time-series. GATE uses a correlation-based clustering algorithm to arrange molecular time-series on a two-dimensional hexagonal array and dynamically colors individual hexagons according to the expression level of the molecular component to which they are assigned, to create animated movies of systems-level molecular regulatory dynamics. In order to infer potential regulatory control mechanisms from patterns of correlation, GATE also allows interactive interrogation of movies against a wide variety of prior knowledge datasets. GATE movies can be paused and are interactive, allowing users to reconstruct networks and perform functional enrichment analyses. Movies created with GATE can be saved in Flash format and can be inserted directly into PDF manuscript files as interactive figures. Availability: GATE is available for download and is free for academic use from http://amp.pharm.mssm.edu/maayan-lab/gate.htm Contact: avi.maayan@mssm.edu 10.1093/bioinformatics/btp628 JF - Bioinformatics TI - GATE: Software for the Analysis and Visualization of High-Dimensional Time-series Expression Data SP - btp628 KW - bioinformatics KW - expression KW - gene KW - proteomics KW - time-course AU - MacArthur, Ben AU - Lachmann, Alexander AU - Lemischka, Ihor AU - Ma'ayan, Avi PY - 2009/11/05/ UR - http://dx.doi.org/10.1093/bioinformatics/btp628 ER -