Ex vivo 3D diffusion tensor imaging and quantification of cardiac laminar structure. Export

@article{citeulike:901962, abstract = {A three-dimensional (3D) diffusion-weighted imaging (DWI) method for measuring cardiac fiber structure at high spatial resolution is presented. The method was applied to the ex vivo reconstruction of the fiber architecture of seven canine hearts. A novel hypothesis-testing method was developed and used to show that distinct populations of secondary and tertiary eigenvalues may be distinguished at reasonable confidence levels (P < or = 0.01) within the canine ventricle. Fiber inclination and sheet angles are reported as a function of transmural depth through the anterior, lateral, and posterior left ventricle (LV) free wall. Within anisotropic regions, two consistent and dominant orientations were identified, supporting published results from histological studies and providing strong evidence that the tertiary eigenvector of the diffusion tensor (DT) defines the sheet normal.}, address = {Center for Cardiovascular Bioinformatics and Modeling, Johns Hopkins University, Baltimore, MD 21218, USA. phelm@bme.jhu.edu}, author = {Helm, Patrick A. and Tseng, Hsiang-Jer J. and Younes, Laurent and McVeigh, Elliot R. and Winslow, Raimond L.}, citeulike-article-id = {901962}, citeulike-linkout-0 = {http://dx.doi.org/10.1002/mrm.20622}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/16149057}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=16149057}, doi = {10.1002/mrm.20622}, issn = {0740-3194}, journal = {Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine}, keywords = {winslow\_talk}, month = {October}, number = {4}, pages = {850--859}, posted-at = {2006-10-17 16:26:36}, priority = {4}, title = {Ex vivo 3D diffusion tensor imaging and quantification of cardiac laminar structure.}, url = {http://dx.doi.org/10.1002/mrm.20622}, volume = {54}, year = {2005} }

TY - JOUR ID - citeulike:901962 L3 - citeulike-article-id:901962 N2 - A three-dimensional (3D) diffusion-weighted imaging (DWI) method for measuring cardiac fiber structure at high spatial resolution is presented. The method was applied to the ex vivo reconstruction of the fiber architecture of seven canine hearts. A novel hypothesis-testing method was developed and used to show that distinct populations of secondary and tertiary eigenvalues may be distinguished at reasonable confidence levels (P < or = 0.01) within the canine ventricle. Fiber inclination and sheet angles are reported as a function of transmural depth through the anterior, lateral, and posterior left ventricle (LV) free wall. Within anisotropic regions, two consistent and dominant orientations were identified, supporting published results from histological studies and providing strong evidence that the tertiary eigenvector of the diffusion tensor (DT) defines the sheet normal. IS - 4 JF - Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine SN - 0740-3194 AD - Center for Cardiovascular Bioinformatics and Modeling, Johns Hopkins University, Baltimore, MD 21218, USA. phelm@bme.jhu.edu EP - 859 TI - Ex vivo 3D diffusion tensor imaging and quantification of cardiac laminar structure. VL - 54 SP - 850 KW - winslow_talk AU - Helm, Patrick AU - Tseng, Hsiang-Jer AU - Younes, Laurent AU - McVeigh, Elliot AU - Winslow, Raimond PY - 2005/10// UR - http://dx.doi.org/10.1002/mrm.20622 ER -