Ionized magnesium in erythrocytes--the best magnesium parameter to observe hypo- or hypermagnesemia. Export

@article{citeulike:1935183, abstract = {BACKGROUND: Almost 99\% of the body magnesium is inside cells. The concentration of intracellular ionized magnesium (iMg) is physiologically relevant. iMg in erythrocytes is a new parameter that can help to establish reliable information on the functional magnesium status. METHODS: iMg concentration in erythrocytes and serum was measured by ion-selective electrode, in clinical analyzer Microlyte (KONE). Total magnesium (tMg) concentration was measured by atomic absorption spectrometry (AAS). Albumin and total protein concentration were measured colorimetrically. RESULTS: In critically ill postoperative patients, the mean of albumin, protein and hematocrit concentration was significantly lower compared to healthy individuals. Hypomagnesemia was found in 15.9\% patients as tMgs, at 22.2\% as iMgs and 36.5\% as iMge. Significant correlations are between iMgs and tMgs or iMge and iMgs/tMgs. In dialyzed patients, the mean of hematocrit was significantly lower, iMge was significantly higher compared with healthy individuals. Significant negative correlations are between iMgs and tMge or iMge/tMge and tMge. CONCLUSIONS: iMge is the best magnesium parameter to observe hypo- or hypermagnesemia for both groups of patients. The function of magnesium is mainly intracellular and intracellular magnesium concentrations can be the method to evaluate the magnesium status.}, address = {Faculty of Chemistry, Warsaw University, Pasteura 1, 02093 Warsaw, Poland.}, author = {Malon, A. and Brockmann, C. and Fijalkowska-Morawska, J. and Rob, P. and Maj-Zurawska, M.}, citeulike-article-id = {1935183}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.cccn.2004.06.006}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/15469857}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=15469857}, doi = {10.1016/j.cccn.2004.06.006}, issn = {0009-8981}, journal = {Clin Chim Acta}, keywords = {ionized, magnesium, test}, month = {November}, number = {1-2}, pages = {67--73}, posted-at = {2007-11-19 03:03:33}, priority = {2}, title = {Ionized magnesium in erythrocytes--the best magnesium parameter to observe hypo- or hypermagnesemia.}, url = {http://dx.doi.org/10.1016/j.cccn.2004.06.006}, volume = {349}, year = {2004} }

TY - JOUR ID - citeulike:1935183 L3 - citeulike-article-id:1935183 N2 - BACKGROUND: Almost 99% of the body magnesium is inside cells. The concentration of intracellular ionized magnesium (iMg) is physiologically relevant. iMg in erythrocytes is a new parameter that can help to establish reliable information on the functional magnesium status. METHODS: iMg concentration in erythrocytes and serum was measured by ion-selective electrode, in clinical analyzer Microlyte (KONE). Total magnesium (tMg) concentration was measured by atomic absorption spectrometry (AAS). Albumin and total protein concentration were measured colorimetrically. RESULTS: In critically ill postoperative patients, the mean of albumin, protein and hematocrit concentration was significantly lower compared to healthy individuals. Hypomagnesemia was found in 15.9% patients as tMgs, at 22.2% as iMgs and 36.5% as iMge. Significant correlations are between iMgs and tMgs or iMge and iMgs/tMgs. In dialyzed patients, the mean of hematocrit was significantly lower, iMge was significantly higher compared with healthy individuals. Significant negative correlations are between iMgs and tMge or iMge/tMge and tMge. CONCLUSIONS: iMge is the best magnesium parameter to observe hypo- or hypermagnesemia for both groups of patients. The function of magnesium is mainly intracellular and intracellular magnesium concentrations can be the method to evaluate the magnesium status. IS - 1-2 JF - Clin Chim Acta SN - 0009-8981 AD - Faculty of Chemistry, Warsaw University, Pasteura 1, 02093 Warsaw, Poland. EP - 73 TI - Ionized magnesium in erythrocytes--the best magnesium parameter to observe hypo- or hypermagnesemia. VL - 349 SP - 67 KW - ionized KW - magnesium KW - test AU - Malon, A AU - Brockmann, C AU - Fijalkowska-Morawska, J AU - Rob, P AU - Maj-Zurawska, M PY - 2004/11// UR - http://dx.doi.org/10.1016/j.cccn.2004.06.006 ER -