Does magnesium sulfate reduce the short- and long-term requirements for pain relief after caesarean delivery? A double-blind placebo-controlled trial. Export

@article{citeulike:5920762, abstract = {OBJECTIVE: The purpose of this study was to determine whether magnesium sulfate decreases postoperative pain and analgesic consumption. STUDY DESIGN: Women who underwent elective cesarean delivery were randomized into groups according to high-dose magnesium sulfate (50 mg/kg load and 2 g/h), low-dose magnesium sulfate (25 mg/kg load and 1 g/h), or placebo. Before the delivery, the dose of patient-controlled opioid that was used and the visual analogs of pain during the first 48 hours after delivery and at 6 weeks were assessed. RESULTS: Forty-two women were assigned randomly to the high-dose arm; 38 women were assigned to the low-dose magnesium arms, and 40 women were assigned to the control arm. The cumulative opioid use (P = .636); pain scores at 6, 12, 24, and 48 hours at rest (P = .786) and with movement (P = .179); the use of analgesics after hospital discharge (P = .711); and wound pain with movement (P = .429) or pressure (P = .144) after 6 weeks were similar. CONCLUSION: Magnesium sulfate does not reduce the severity of short-term or long-term (6 weeks) pain after cesarean delivery.}, author = {Paech, Michael J. and Magann, Everett F. and Doherty, Dorota A. and Verity, Lisa J. and Newnham, John P.}, citeulike-article-id = {5920762}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.ajog.2006.01.009}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/16615926}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=16615926}, doi = {10.1016/j.ajog.2006.01.009}, issn = {1097-6868}, journal = {American journal of obstetrics and gynecology}, keywords = {anesthesia, magnesium}, month = {June}, number = {6}, posted-at = {2009-10-11 10:13:12}, priority = {2}, title = {Does magnesium sulfate reduce the short- and long-term requirements for pain relief after caesarean delivery? A double-blind placebo-controlled trial.}, url = {http://dx.doi.org/10.1016/j.ajog.2006.01.009}, volume = {194}, year = {2006} }

TY - JOUR ID - citeulike:5920762 L3 - citeulike-article-id:5920762 N2 - OBJECTIVE: The purpose of this study was to determine whether magnesium sulfate decreases postoperative pain and analgesic consumption. STUDY DESIGN: Women who underwent elective cesarean delivery were randomized into groups according to high-dose magnesium sulfate (50 mg/kg load and 2 g/h), low-dose magnesium sulfate (25 mg/kg load and 1 g/h), or placebo. Before the delivery, the dose of patient-controlled opioid that was used and the visual analogs of pain during the first 48 hours after delivery and at 6 weeks were assessed. RESULTS: Forty-two women were assigned randomly to the high-dose arm; 38 women were assigned to the low-dose magnesium arms, and 40 women were assigned to the control arm. The cumulative opioid use (P = .636); pain scores at 6, 12, 24, and 48 hours at rest (P = .786) and with movement (P = .179); the use of analgesics after hospital discharge (P = .711); and wound pain with movement (P = .429) or pressure (P = .144) after 6 weeks were similar. CONCLUSION: Magnesium sulfate does not reduce the severity of short-term or long-term (6 weeks) pain after cesarean delivery. IS - 6 JF - American journal of obstetrics and gynecology SN - 1097-6868 TI - Does magnesium sulfate reduce the short- and long-term requirements for pain relief after caesarean delivery? A double-blind placebo-controlled trial. VL - 194 KW - anesthesia KW - magnesium AU - Paech, Michael AU - Magann, Everett AU - Doherty, Dorota AU - Verity, Lisa AU - Newnham, John PY - 2006/06// UR - http://dx.doi.org/10.1016/j.ajog.2006.01.009 ER -