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Integrating molecular and network biology to decode endocytosis. Export

Nature, Vol. 448, No. 7156. (23 August 2007), pp. 883-888.

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biology cell chamical_reaction network

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The strength of network biology lies in its ability to derive cell biological information without a priori mechanistic or molecular knowledge. It is shown here how a careful understanding of a given biological pathway can refine an interactome approach. This permits the elucidation of additional design principles and of spatio-temporal dynamics behind pathways, and aids in experimental design and interpretation.


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