FAIR true-FISP perfusion imaging of the kidneys Export

@article{citeulike:1402701, abstract = {Most arterial spin labeling (ASL) techniques apply echoplanar imaging (EPI) because this strategy provides relatively high SNR in short measuring times. Unfortunately, those techniques are very susceptible to static magnetic field inhomogeneities and perfusion signals from organs with fast transverse relaxation might decrease due to the exchange of water molecules in capillaries and organ tissue combined with relatively long echo times of EPI sequences. To overcome these problems a novel imaging technique, FAIR True-FISP, was developed. It combines a FAIR (flow-sensitive alternating inversion recovery) perfusion preparation and a true fast imaging with steady precession (True-FISP) data acquisition strategy. True-FISP was chosen since this sequence type does not show the mentioned disadvantages of EPI, but provides a similar SNR per measuring time. An important problem of this approach is that True-FISP sequences usually work in a steady state which is independent of a previous preparation of magnetization. For this reason a sequence structure had to be developed which keeps the advantages of True-FISP and makes the signal intensity sensitive to the FAIR preparation. Breathhold and nonbreathhold examinations of kidneys are presented and possible strategies to quantitative flow measurements are reported. It is shown that correction of spatially inhomogeneous receiver coil characteristics is easily feasible and leads to clinically valuable perfusion examinations of kidneys without application of potentially nephrotoxic contrast media. Magn Reson Med 51:353-361, 2004. {\copyright} 2004 Wiley-Liss, Inc.}, address = {Section on Experimental Radiology, Department of Diagnostic Radiology, University of T\"{u}bingen, Germany; Section for Experimental MR of the CNS, Department of Neuroradiology, University of T\"{u}bingen, Germany}, author = {Martirosian, Petros and Klose, Uwe and Mader, Irina and Schick, Fritz}, citeulike-article-id = {1402701}, citeulike-linkout-0 = {http://dx.doi.org/10.1002/mrm.10709}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/14755661}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=14755661}, citeulike-linkout-3 = {http://www3.interscience.wiley.com/cgi-bin/abstract/107063862/ABSTRACT}, doi = {10.1002/mrm.10709}, journal = {Magnetic Resonance in Medicine}, keywords = {45, 5, acidity, blood, filter, imaging, minerals, minutes, pressure, quarts, water}, number = {2}, pages = {353--361}, posted-at = {2009-03-10 09:03:59}, priority = {2}, title = {FAIR true-FISP perfusion imaging of the kidneys}, url = {http://dx.doi.org/10.1002/mrm.10709}, volume = {51}, year = {2004} }

TY - JOUR ID - citeulike:1402701 L3 - citeulike-article-id:1402701 N2 - Most arterial spin labeling (ASL) techniques apply echoplanar imaging (EPI) because this strategy provides relatively high SNR in short measuring times. Unfortunately, those techniques are very susceptible to static magnetic field inhomogeneities and perfusion signals from organs with fast transverse relaxation might decrease due to the exchange of water molecules in capillaries and organ tissue combined with relatively long echo times of EPI sequences. To overcome these problems a novel imaging technique, FAIR True-FISP, was developed. It combines a FAIR (flow-sensitive alternating inversion recovery) perfusion preparation and a true fast imaging with steady precession (True-FISP) data acquisition strategy. True-FISP was chosen since this sequence type does not show the mentioned disadvantages of EPI, but provides a similar SNR per measuring time. An important problem of this approach is that True-FISP sequences usually work in a steady state which is independent of a previous preparation of magnetization. For this reason a sequence structure had to be developed which keeps the advantages of True-FISP and makes the signal intensity sensitive to the FAIR preparation. Breathhold and nonbreathhold examinations of kidneys are presented and possible strategies to quantitative flow measurements are reported. It is shown that correction of spatially inhomogeneous receiver coil characteristics is easily feasible and leads to clinically valuable perfusion examinations of kidneys without application of potentially nephrotoxic contrast media. Magn Reson Med 51:353-361, 2004. © 2004 Wiley-Liss, Inc. IS - 2 JF - Magnetic Resonance in Medicine AD - Section on Experimental Radiology, Department of Diagnostic Radiology, University of Tübingen, Germany; Section for Experimental MR of the CNS, Department of Neuroradiology, University of Tübingen, Germany EP - 361 TI - FAIR true-FISP perfusion imaging of the kidneys VL - 51 SP - 353 KW - 45 KW - 5 KW - acidity KW - blood KW - filter KW - imaging KW - minerals KW - minutes KW - pressure KW - quarts KW - water AU - Martirosian, Petros AU - Klose, Uwe AU - Mader, Irina AU - Schick, Fritz PY - 2004/// UR - http://dx.doi.org/10.1002/mrm.10709 ER -