Neurophysiological indices of CNS plasticity in the course of treatment of head trauma in adolescents Export

@article{citeulike:3730722, abstract = {Abstract\ \ Using the methods of quantitative EEG analysis and cognitive evoked potentials, we investigated delayed consequences of head trauma (HT) after nootropic therapy with cerebrolysin. The study was performed in 30 12-to 19-year-old adolescents who had had severe HT with brain contusion one to five years prior to the study and manifested asthenic symptoms. During the study, they underwent treatment with 30 daily intramuscular injections of cerebrolysin at a dose of 0.1 ml/kg body weight. A positive effect on the functional state of the brain was found in 77\% of patients. It was expressed as the appearance of the occipital α rhythm in the EEGs, an increase in the EEG spectral power, normalization of frequency parameters of the α rhythm, a decrease in the power spectrum of the low-frequency θ and δ EEG activity, and shortening of the P300 peak latency. These changes were associated with an improvement of the general clinical state and the psychometric indices of attention and memory in the patients.}, author = {Iznak, A. and Iznak, E. and Zavadenko, N. and Guzilova, L.}, citeulike-article-id = {3730722}, citeulike-linkout-0 = {http://dx.doi.org/10.1134/S0362119708060030}, citeulike-linkout-1 = {http://www.springerlink.com/content/945t7j5t8lm3k031}, day = {1}, doi = {10.1134/S0362119708060030}, journal = {Human Physiology}, keywords = {ado, attention, cns, eeg, ht, memory, p300}, month = {November}, number = {6}, pages = {672--677}, posted-at = {2009-03-04 12:20:20}, priority = {2}, title = {Neurophysiological indices of CNS plasticity in the course of treatment of head trauma in adolescents}, url = {http://dx.doi.org/10.1134/S0362119708060030}, volume = {34}, year = {2008} }

TY - JOUR ID - citeulike:3730722 L3 - citeulike-article-id:3730722 N2 - Abstract  Using the methods of quantitative EEG analysis and cognitive evoked potentials, we investigated delayed consequences of head trauma (HT) after nootropic therapy with cerebrolysin. The study was performed in 30 12-to 19-year-old adolescents who had had severe HT with brain contusion one to five years prior to the study and manifested asthenic symptoms. During the study, they underwent treatment with 30 daily intramuscular injections of cerebrolysin at a dose of 0.1 ml/kg body weight. A positive effect on the functional state of the brain was found in 77% of patients. It was expressed as the appearance of the occipital α rhythm in the EEGs, an increase in the EEG spectral power, normalization of frequency parameters of the α rhythm, a decrease in the power spectrum of the low-frequency θ and δ EEG activity, and shortening of the P300 peak latency. These changes were associated with an improvement of the general clinical state and the psychometric indices of attention and memory in the patients. IS - 6 JF - Human Physiology EP - 677 TI - Neurophysiological indices of CNS plasticity in the course of treatment of head trauma in adolescents VL - 34 SP - 672 KW - ado KW - attention KW - cns KW - eeg KW - ht KW - memory KW - p300 AU - Iznak, A AU - Iznak, E AU - Zavadenko, N AU - Guzilova, L PY - 2008/11/01/ UR - http://dx.doi.org/10.1134/S0362119708060030 ER -