Rodent models for autism: A critical review Export

@article{citeulike:2205948, abstract = {We review 15 rodent models proposed for exploring autistic behaviours. There are two main types of behavioural tests that are relevant to autism, these include tests of social behaviour and communication and tests of stereotypy and cognitive rigidity. Only few of these models have been tested for both of these types of behaviours. Furthermore, very few attempts have been made to test medications known to improve certain symptoms of patients. Finally, potential transgenic mouse models in addition to toxic and lesion models are discussed.Section editor: Per Lindahl - Wallenberg Laboratory for Cardiovascular Research, Goteborg University, Sweden}, author = {Belzung, Catherine and Leman, Samuel and Vourc'h, Patrick and Andres, Christian}, citeulike-article-id = {2205948}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.ddmod.2005.05.004}, citeulike-linkout-1 = {http://www.sciencedirect.com/science/article/B75D8-4GCXBPC-3/2/a038c0d35c23872a501aefb6ad95d1c0}, doi = {10.1016/j.ddmod.2005.05.004}, journal = {Drug Discovery Today: Disease Models}, keywords = {autism, drugs, mice, model, rats, review}, month = {}, number = {2}, pages = {93--101}, posted-at = {2008-01-08 01:30:22}, priority = {2}, title = {Rodent models for autism: A critical review}, url = {http://dx.doi.org/10.1016/j.ddmod.2005.05.004}, volume = {2}, year = {2005} }

TY - JOUR ID - citeulike:2205948 L3 - citeulike-article-id:2205948 N2 - We review 15 rodent models proposed for exploring autistic behaviours. There are two main types of behavioural tests that are relevant to autism, these include tests of social behaviour and communication and tests of stereotypy and cognitive rigidity. Only few of these models have been tested for both of these types of behaviours. Furthermore, very few attempts have been made to test medications known to improve certain symptoms of patients. Finally, potential transgenic mouse models in addition to toxic and lesion models are discussed.Section editor: Per Lindahl - Wallenberg Laboratory for Cardiovascular Research, Goteborg University, Sweden IS - 2 JF - Drug Discovery Today: Disease Models EP - 101 TI - Rodent models for autism: A critical review VL - 2 SP - 93 KW - autism KW - drugs KW - mice KW - model KW - rats KW - review AU - Belzung, Catherine AU - Leman, Samuel AU - Vourc'h, Patrick AU - Andres, Christian PY - 2005/0// UR - http://dx.doi.org/10.1016/j.ddmod.2005.05.004 ER -