A genetic history questionnaire-based system in primary prenatal care to screen for selected fetal disorders. Export

@article{citeulike:1822056, abstract = {DNA (and other) diagnostic tests are now available for a number of serious, but uncommon, fetal disorders. We designed and evaluated a screening system for this purpose in primary care, coupled with targeted information for practitioners and patients. We developed a 15-question family history form for completion by office staff or patients, addressing conditions for which definitive diagnosis was available, linked to secondary questionnaires to follow up on "yes" answers. Guidelines for assessing risk, follow-up recommendations, and information resources were also linked. Following pilot testing, this screening system was introduced throughout Maine. We enrolled 212 providers (85-90\% of the state's pregnancies). In a subsequent survey, 85\% of the practices were screening all new patients and 3\% some; 12\% did not use the system. Time for form completion averaged 7 min. Overall, provider satisfaction was 4.4 on a five-point scale. Patients responded favorably; a minority was anxious or overwhelmed. Total referral calls to Maine's genetic/perinatal centers did not increase, but calls about family history of genetic disorders or maternal conditions increased significantly. This screening system for guiding appropriate use of DNA (and other) testing in pregnancy can be used successfully in primary care.}, address = {Foundation for Blood Research, Scarborough, Maine., Present address: National Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, Georgia.}, author = {Bradley, L. A. and Kloza, E. M. and Haddow, P. K. and Beauregard, L. J. and Johnson, J. L. and Haddow, J. E.}, citeulike-article-id = {1822056}, citeulike-linkout-0 = {http://dx.doi.org/10.1089/gte.2007.0009}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/17949290}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=17949290}, doi = {10.1089/gte.2007.0009}, issn = {1090-6576}, journal = {Genet Test}, keywords = {assessment, fetal-disorders, genetics, pgp, prenatal-care, screening}, number = {3}, pages = {291--295}, posted-at = {2007-10-25 23:56:04}, priority = {2}, title = {A genetic history questionnaire-based system in primary prenatal care to screen for selected fetal disorders.}, url = {http://dx.doi.org/10.1089/gte.2007.0009}, volume = {11}, year = {2007} }

TY - JOUR ID - citeulike:1822056 L3 - citeulike-article-id:1822056 N2 - DNA (and other) diagnostic tests are now available for a number of serious, but uncommon, fetal disorders. We designed and evaluated a screening system for this purpose in primary care, coupled with targeted information for practitioners and patients. We developed a 15-question family history form for completion by office staff or patients, addressing conditions for which definitive diagnosis was available, linked to secondary questionnaires to follow up on "yes" answers. Guidelines for assessing risk, follow-up recommendations, and information resources were also linked. Following pilot testing, this screening system was introduced throughout Maine. We enrolled 212 providers (85-90% of the state's pregnancies). In a subsequent survey, 85% of the practices were screening all new patients and 3% some; 12% did not use the system. Time for form completion averaged 7 min. Overall, provider satisfaction was 4.4 on a five-point scale. Patients responded favorably; a minority was anxious or overwhelmed. Total referral calls to Maine's genetic/perinatal centers did not increase, but calls about family history of genetic disorders or maternal conditions increased significantly. This screening system for guiding appropriate use of DNA (and other) testing in pregnancy can be used successfully in primary care. IS - 3 JF - Genet Test SN - 1090-6576 AD - Foundation for Blood Research, Scarborough, Maine., Present address: National Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, Georgia. EP - 295 TI - A genetic history questionnaire-based system in primary prenatal care to screen for selected fetal disorders. VL - 11 SP - 291 KW - assessment KW - fetal-disorders KW - genetics KW - pgp KW - prenatal-care KW - screening AU - Bradley, LA AU - Kloza, EM AU - Haddow, PK AU - Beauregard, LJ AU - Johnson, JL AU - Haddow, JE PY - 2007/// UR - http://dx.doi.org/10.1089/gte.2007.0009 ER -