Cyclin E in human cancers. Export

@article{citeulike:3847280, abstract = {Regulators of the cell cycle such as cyclin E play an important part in neoplasia. The cyclin E protein forms a partnership with a specific protein kinase. This complex phosphorylates key substrates to initiate DNA synthesis. Cyclin-dependent kinase inhibitors (CKIs) are able to suppress the activity of cyclin E. Various substances (including proteins produced by oncogenic viruses) affect cyclin E directly or indirectly through an interaction with CKIs. These interactions are important in elucidating the mechanisms of neoplasia. They may also provide prognostic information in a wide range of common cancers. Cyclin E may even be a target for treatment of cancers in the future.}, author = {Donnellan, R. and Chetty, R.}, citeulike-article-id = {3847280}, citeulike-linkout-0 = {http://view.ncbi.nlm.nih.gov/pubmed/10224221}, citeulike-linkout-1 = {http://www.hubmed.org/display.cgi?uids=10224221}, issn = {0892-6638}, journal = {The FASEB journal : official publication of the Federation of American Societies for Experimental Biology}, keywords = {cancer, cycline, review}, month = {May}, number = {8}, pages = {773--780}, posted-at = {2009-01-04 14:48:12}, priority = {2}, title = {Cyclin E in human cancers.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/10224221}, volume = {13}, year = {1999} }

TY - JOUR ID - citeulike:3847280 L3 - citeulike-article-id:3847280 N2 - Regulators of the cell cycle such as cyclin E play an important part in neoplasia. The cyclin E protein forms a partnership with a specific protein kinase. This complex phosphorylates key substrates to initiate DNA synthesis. Cyclin-dependent kinase inhibitors (CKIs) are able to suppress the activity of cyclin E. Various substances (including proteins produced by oncogenic viruses) affect cyclin E directly or indirectly through an interaction with CKIs. These interactions are important in elucidating the mechanisms of neoplasia. They may also provide prognostic information in a wide range of common cancers. Cyclin E may even be a target for treatment of cancers in the future. IS - 8 JF - The FASEB journal : official publication of the Federation of American Societies for Experimental Biology SN - 0892-6638 EP - 780 TI - Cyclin E in human cancers. VL - 13 SP - 773 KW - cancer KW - cycline KW - review AU - Donnellan, R AU - Chetty, R PY - 1999/05// UR - http://view.ncbi.nlm.nih.gov/pubmed/10224221 ER -