The many phases of anaphase. Export

@article{citeulike:4004895, abstract = {Anaphase is the stage of the cell cycle in which duplicated chromosomes separate and move towards opposite poles of the cell. Although its chromosome movements have always been viewed as majestic, until recently anaphase lacked obvious landmarks of regulation. The picture has changed with numerous recent studies that have highlighted the raison d'\^{e}tre of anaphase. It is now known to be associated with a series of regulatory pathways that promote a switch from high to low cyclin-dependent kinase activity--an essential feature for proper mitotic exit. The balance between protein phosphorylation and protein dephosphorylation drives and coordinates diverse processes such as chromosome movement, spindle dynamics and cleavage furrow formation. This well-ordered sequence of events is central to successful mitosis.}, author = {de Gramont, A. and Cohen-Fix, O.}, citeulike-article-id = {4004895}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.tibs.2005.08.008}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/16126387}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=16126387}, doi = {10.1016/j.tibs.2005.08.008}, issn = {0968-0004}, journal = {Trends in biochemical sciences}, keywords = {activity, anaphase, cdk, mitosis, review}, month = {October}, number = {10}, pages = {559--568}, posted-at = {2009-02-04 01:55:53}, priority = {2}, title = {The many phases of anaphase.}, url = {http://dx.doi.org/10.1016/j.tibs.2005.08.008}, volume = {30}, year = {2005} }

TY - JOUR ID - citeulike:4004895 L3 - citeulike-article-id:4004895 N2 - Anaphase is the stage of the cell cycle in which duplicated chromosomes separate and move towards opposite poles of the cell. Although its chromosome movements have always been viewed as majestic, until recently anaphase lacked obvious landmarks of regulation. The picture has changed with numerous recent studies that have highlighted the raison d'être of anaphase. It is now known to be associated with a series of regulatory pathways that promote a switch from high to low cyclin-dependent kinase activity--an essential feature for proper mitotic exit. The balance between protein phosphorylation and protein dephosphorylation drives and coordinates diverse processes such as chromosome movement, spindle dynamics and cleavage furrow formation. This well-ordered sequence of events is central to successful mitosis. IS - 10 JF - Trends in biochemical sciences SN - 0968-0004 EP - 568 TI - The many phases of anaphase. VL - 30 SP - 559 KW - activity KW - anaphase KW - cdk KW - mitosis KW - review AU - de Gramont, A AU - Cohen-Fix, O PY - 2005/10// UR - http://dx.doi.org/10.1016/j.tibs.2005.08.008 ER -