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A comparison of MSA tools. Export

Bioinformation, Vol. 2, No. 10. (2008), pp. 452-455.

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algorithm alignment proj_assembly proj_interprets review validation

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Claims not a significantly large difference in quality between alignment methods.

chad_davis (public note) - 2008-10-20 12:22:03

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Multiple sequence alignment (MSA) is essential in phylogenetic, evolutionary and functional analysis. Several MSA tools are available in the literature. Here, we use several MSA tools such as ClustalX, Align-m, T-Coffee, SAGA, ProbCons, MAFFT, MUSCLE and DIALIGN to illustrate comparative phylogenetic trees analysis for two datasets. Results show that there is no single MSA tool that consistently outperforms the rest in producing reliable phylogenetic trees.


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