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Electron tomography: towards visualizing the molecular organization of the cytoplasm. Export

Curr Opin Struct Biol, Vol. 12, No. 5. (October 2002), pp. 679-684.

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mpi structure

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Electron tomography of thin sections of plastic-embedded biological material provides valuable insights into the organellar organization of cells. With the advent of automated data-acquisition procedures, it has become possible to study radiation-sensitive specimens, such as frozen-hydrated organelles and whole cells. This opens up exciting perspectives for visualizing the molecular organization of the cytoplasm.


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