Residual cognitive impairments in remitted depressed patients. Export

@article{citeulike:3151843, abstract = {Depressive disorders are associated with various cognitive impairments. Studies on whether or not these impairments persist into the euthymic phase have shown conflicting results, due to differences in test versions and in study samples. In this paper, we aimed to compare the cognitive performance of remitted depressed patients with that of age- and gender-matched healthy volunteers across a wide range of cognitive domains. In two studies, we found few differences on neutral as well as emotional information processing tests. The findings indicate that remitted depressed patients who use antidepressant medication still show an increased recognition of facial expression of fear compared to healthy controls. Patients also performed worse on a test of recognition of abstract visual information from long-term memory. No other residual cognitive impairments were found. These results indicate that most of the cognitive impairments associated with depression resolve with recovery through medication, even when recovery is incomplete. Considering the finding that remitted depressed patients have higher levels of cognitive reactivity, future studies may investigate the possibility that these cognitive impairments have not resolved but have become latent, and may therefore easily be triggered by small changes in mood state.}, address = {Institute for Psychological Research, Leiden University, Leiden, The Netherlands.}, author = {Merens, W. and Booij, L. and Van Der Does, A. J.}, citeulike-article-id = {3151843}, citeulike-linkout-0 = {http://dx.doi.org/10.1002/da.20391}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/18008314}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=18008314}, doi = {10.1002/da.20391}, issn = {1520-6394}, journal = {Depression and anxiety}, keywords = {cognition, depression, information-processing, remitted}, number = {6}, posted-at = {2008-08-24 07:41:26}, priority = {3}, title = {Residual cognitive impairments in remitted depressed patients.}, url = {http://dx.doi.org/10.1002/da.20391}, volume = {25}, year = {2008} }

TY - JOUR ID - citeulike:3151843 L3 - citeulike-article-id:3151843 N2 - Depressive disorders are associated with various cognitive impairments. Studies on whether or not these impairments persist into the euthymic phase have shown conflicting results, due to differences in test versions and in study samples. In this paper, we aimed to compare the cognitive performance of remitted depressed patients with that of age- and gender-matched healthy volunteers across a wide range of cognitive domains. In two studies, we found few differences on neutral as well as emotional information processing tests. The findings indicate that remitted depressed patients who use antidepressant medication still show an increased recognition of facial expression of fear compared to healthy controls. Patients also performed worse on a test of recognition of abstract visual information from long-term memory. No other residual cognitive impairments were found. These results indicate that most of the cognitive impairments associated with depression resolve with recovery through medication, even when recovery is incomplete. Considering the finding that remitted depressed patients have higher levels of cognitive reactivity, future studies may investigate the possibility that these cognitive impairments have not resolved but have become latent, and may therefore easily be triggered by small changes in mood state. IS - 6 JF - Depression and anxiety SN - 1520-6394 AD - Institute for Psychological Research, Leiden University, Leiden, The Netherlands. TI - Residual cognitive impairments in remitted depressed patients. VL - 25 KW - cognition KW - depression KW - information-processing KW - remitted AU - Merens, W AU - Booij, L AU - Van Der Does, AJ PY - 2008/// UR - http://dx.doi.org/10.1002/da.20391 ER -