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DM-nitrophen AM is caged magnesium Export

Cell Calcium, Vol. 39, No. 6. (June 2006), pp. 471-473.

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am cage caged calcium compound dm-nitrophen magnesium

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DM-nitrophen is a photolabile derivative of EDTA and therefore functions as either caged Ca 2+ or caged Mg 2+ . Several papers have been published recently which use the AM ester to load intact cells with DM-nitrophen; under these conditions it is caged Mg 2+ . In this commentary, I give a short history of the development and application of caged Ca 2+ probes, explaining why EGTA and BAPTA-based Ca 2+ cages are to be preferred for the photorelease of Ca 2+ under normal intracellular conditions.


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